Sökning: "protein pre-fractionation"

Hittade 4 avhandlingar innehållade orden protein pre-fractionation.

  1. 1. Separation Methods in Membrane Proteomics -Integration of Aqueous Two-Phase Partitioning for Enrichment and Pre-Fractionation

    Författare :Henrik Everberg; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Proteins; metabolism; Biokemi; Metabolism; Biochemistry; Aqueous two-phase partitioning; enzymology; Proteiner; enzymologi; Proteomics;

    Sammanfattning : The study of the protein complement of a genome is called proteomics. Proteomics can be defined as identification, quantification and characterization of a total set of proteins expressed at different time-points or under different cellular states to provide global information about biological processes. LÄS MER

  2. 2. In search of diagnostic and prognostic markers for thyroid cancer : a proteomics approach

    Författare :Anastasios Sofiadis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Thyroid tumors; thyroid proteomics; S100A6; MIB-1; 2DE; MALDI-TOF-MS; SELDI-TOF-MS; protein pre-fractionation;

    Sammanfattning : Early diagnosis of cancer can influence the therapeutic strategy increasing the chances of cure or, at least, prolonged survival. It is equally important to be able to detect prognostic signs, i.e. tumor features that characterize its behavior. LÄS MER

  3. 3. Clinical proteomics : quantitative analysis and biological interpretation

    Författare :AnnSofi Sandberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The main expectations of applying proteomics technologies to clinical questions are the discovery of disease related biomarkers. Despite technological advancement to increase proteome coverage and depth to meet these expectations the number of generated biomarkers for clinical use is small. LÄS MER

  4. 4. Quality Control for high-throughput Quantitative Proteomics - Harnessing the potential of label-free LC-MS

    Författare :Marianne Sandin; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; mass spectrometry; quality control; data analysis; label-free; feature detection; alignment; biomarker discovery; separation techniques;

    Sammanfattning : Multiplex protein quantification, proteomics, is essential for uncovering new biomarkers and understanding biology. Liquid chromatography coupled to mass spectrometry (LC-MS) is the predominant technique for these measurements. LÄS MER