Sökning: "protein dynamics"
Visar resultat 6 - 10 av 482 avhandlingar innehållade orden protein dynamics.
6. Water and protein solutions studied by field-dependent magnetic relaxation
Sammanfattning : In the work presented, nuclear magnetic resonance (NMR) relaxation is used to study wide range of systems. The thesis concerns solvent interactions studied with relaxation techniques that involve measurements at many fields, which allows the separation of individual relaxation mechanisms. LÄS MER
7. Water and Protein Dynamics in Biological Systems Studied by Magnetic Relaxation Dispersion
Sammanfattning : The results presented in this thesis demonstrate that the magnetic relaxation dispersion (MRD) technique can provide information of relevance to protein biophysics, magnetic resonance imaging and cell biology. By immobilizing proteins with covalent cross-links, intermittent protein dynamics on the previously inaccessible ns-µs time scale could be probed with MRD via the exchange of water molecules between internal cavities and the surrounding bulk solvent phase. LÄS MER
8. Biophysical characterization of protein-protein interactions involving intrinsically disordered proteins
Sammanfattning : Intrinsically disordered proteins and regions (IDPs/Rs) are proteins that do not form stable and well-defined structures in their free states but rather occupy an ensemble of conformations that change over time while still staying functional. They are prevalent in the eukaryotic proteome and are involved in various vital processes in the cell where they often interact with their binding partners through coupled binding and folding reactions. LÄS MER
9. Polymer and Protein Physics : Simulations of Interactions and Dynamics
Sammanfattning : Proteins can, without any exaggeration, be called the "building blocks of life". Their physical properties depend not only on the chemical structure but also on their geometric shape. In this thesis, I investigate protein geometry using several different methods.We start with a coarse-graining model to study the general behavior of polymers. LÄS MER
10. Exploring the Molecular Dynamics of Proteins and Viruses
Sammanfattning : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. LÄS MER