Sökning: "prostate-specific antigen"

Visar resultat 21 - 25 av 85 avhandlingar innehållade orden prostate-specific antigen.

1. 21. Tissue prostatic specific antigen (T-PSA) : a way to predict and understand the development of prostate cancer

   Författare :Mirtha Grande; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Tissue PSA; aspiration biopsies; estrogens; ecNOS mRNA expression; ET1 mRNA expression; LNCaP-FGC; LNCaP-r.;

   Sammanfattning : Prostate cancer (CaP) is the most prevalent malignancy among men in Sweden. One major problem associated with CaP is the choice of treatment since the disease may develop very differently from patient to patient. Many efforts have focused on the development of markers for prognosis and monitoring treatment affecting the endocrine system of CaP. LÄS MER

3. 22. Tissue biomarkers in prostate cancer

   Författare :Sara Jonmarker Jaraj; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely immersed in formalin overnight. Formalin may also be injected into the prostate for improved fixation. LÄS MER

4. 23. Generation of Therapeutic T Cells for Prostate Cancer

   Författare :Ole Forsberg; Magnus Essand; Thomas Tötterman; Gustav Gaudernack; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; T cells; dendritic cells; peptides; cytomegalovirus; adenovirus; immunotherapy; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : The work presented herein focuses on the activation of the adaptive immune system in order to develop T cell-based immunotherapy for viral infections and cancer. The main goal was to identify and activate viral or tumoral antigen-specific T cells by using different identification, isolation and stimulation techniques. LÄS MER

5. 24. Some Characteristics of Human Prostasomes and Their Relationship to Prostate Cancer

   Författare :Göran Ronquist; Anders Larsson; Lena Carlsson; Alicia Llorente; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostasomes; prostate; prostate cancer; clusterin; antibodies; metastasis; exosomes; PC-3 cells; DNA vehicles; gene therapy; immunoblotting; mass spectrometry; agarose gel electrophoresis; vertebral metastasis.; Clinical chemistry; Klinisk kemi; Clinical Chemistry; klinisk kemi;

   Sammanfattning : Background: The secretory epithelial cells of the prostate gland use sophisticated vehicles named prostasomes to relay important information to sperm cells in semen. This prostasome-forming and secretory ability of the epithelial cells is also preserved in poorly differentiated prostate cancer cells. LÄS MER

7. 25. Biomarker detection via lab-on-a-chip integrated immunoaffinity approach for fluorescence and mass spectrometry readout

   Författare :Asilah Ahmad Tajudin; Avdelningen för Biomedicinsk teknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; immunoaffinity; affinity prefractionation; immunoMALDI; solid-phase extraction; protein digestion; ISET; antibody microarray; signal amplification; fluorescence; microfluidics; lab on a chip; separation; acoustophoresis; ultrasound; acoustic radiation force; plasma; proteomics; MALDI mass spectrometry; immunoassay; porous silicon.;

   Sammanfattning : The blood/plasma protein biomarker profile represents the pathological and physiological changes relating to human diseases. However, the plasma proteome reflects a high degree of complexity that results in a challenge for most analytical methods in clinical diagnostics. LÄS MER