Sökning: "prostate-specific antigen"

Visar resultat 16 - 20 av 66 avhandlingar innehållade orden prostate-specific antigen.

  1. 16. Induction of t-cell responses against PSA by plasmid DNA immunization

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Författare :Maxim Pavlenko; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate-specific antigen; DNA vaccine; cytotoxic T lymphocytes;

    Sammanfattning : This thesis is focused on using plasmid DNA encoding human prostate-specific antigen (PSA) for immunotherapy of prostate cancer. PSA is a secreted serine protease, which is produced almost exclusively by prostate epithelial cells. LÄS MER

  2. 17. The Multiple Faces of Genetically-Modified T Cells Potential Applications in Therapy

    Detta är en avhandling från Uppsala : Uppsala universitet

    Författare :Victoria Hillerdal; Uppsala universitet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; genetically engineered T cells; chimeric antigen receptor; T cell receptor; antigen-specific T cells; immunotherapy; Immunologi; Immunology; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. LÄS MER

  3. 18. Delivery of DNA vaccines against cancer

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Författare :Anna-Karin Roos; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA vaccine; prostate-specific antigen; immunotherapy; prostate cancer; electroporation;

    Sammanfattning : DNA vaccines against cancer have shown promising results in animal models. Efficient antigenspecific T cell responses and tumor protection have been demonstrated after vaccination with DNA encoding tumor antigens in mice. LÄS MER

  4. 19. Tissue prostatic specific antigen (T-PSA) : A way to predict and understand the development of prostate cancer

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Sciences

    Författare :Mirtha Grande; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue PSA; aspiration biopsies; estrogens; ecNOS mRNA expression; ET1 mRNA expression; LNCaP-FGC; LNCaP-r.;

    Sammanfattning : Prostate cancer (CaP) is the most prevalent malignancy among men in Sweden. One major problem associated with CaP is the choice of treatment since the disease may develop very differently from patient to patient. Many efforts have focused on the development of markers for prognosis and monitoring treatment affecting the endocrine system of CaP. LÄS MER

  5. 20. Tissue biomarkers in prostate cancer

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Författare :Sara Jonmarker Jaraj; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely immersed in formalin overnight. Formalin may also be injected into the prostate for improved fixation. LÄS MER