Sökning: "propranolol"

Visar resultat 16 - 20 av 41 avhandlingar innehållade ordet propranolol.

  1. 16. New Techniques for Chiral Separations

    Författare :Jeanette Olsson; Lars Blomberg; Steen Honoré Hansen; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; analytical chemistry; chiral separation; GC; CE; CEC; Analytical chemistry; Analytisk kemi; Kemi; Chemistry;

    Sammanfattning : Gas chromatography (GC) has been utilized for the study of enantiomer resolution of the atropisomers of PCBs, o,p´-DDD and o,p´-DDT. Different substituents and concentrations of cyclodextrin, capillary dimensions and type of stationary phase films have been investigated to achieve the resolution of as many of the atropisomers on one column as possible. LÄS MER

  3. 17. Significance of serotonin for pain, allodynia, and hyperalgesia in the human masseter muscle

    Författare :Malin Ernberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Anxiety; Double-Blind Method; 5-Hydroxytryptamine; Fibromyalgia; Hyperalgesia; Masseter muscle; Microdialysis; Pain threshold; Visual Analogue Pain Scale;

    Sammanfattning : The main aim of this thesis was to investigate the hypothesis that serotonin (5-HT) is involved in the pathophysiology of human chronic muscle pain. The thesis comprises a clinical and a human experimental part. LÄS MER

  4. 18. Determination of the Environmental Fate of Drug Substances and the Matrix Effects of Complex Samples in SFC/ESI-MS

    Författare :Alfred Haglind; Curt Pettersson; Mikael Hedeland; Torbjörn Arvidsson; Deirdre Cabooter; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SFC-MS; matrix effect; ion cluster; Supercritical fluid chromatography; ESI; chiral separation; transformation products; LC-QToF; wetland microcosms; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Sammanfattning : Awareness of the potential problems caused by drug compounds in the environment has increased over the last decade, both among researchers and with the public. This thesis describes the development of analytical methods and their application to wetlands constructed for purification of wastewater from e.g. drug compounds. LÄS MER

  5. 19. Pharmacodynamic modeling of cardiovascular effects of Σb-antagonists and moxonidine : Special emphasis on tolerance and rebound effects

    Författare :Lena Brynne; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; Biopharmaceutics; biofarmaci;

    Sammanfattning : Pharmacodynamic (PD) modeling was used to characterize and quantify the short- and long-term changes in cardiovascular effects following treatment with β-antagonists or imidazoline receptor agonist moxonidine, in spontaneous hypertensive rats and patients with congestive heart failure, respectively. The complex cardiovascular system is regulated by several feedback mechanisms with different time domains and gains. LÄS MER

  7. 20. The contribution of proteins and lipids to COPI vesicle formation and consumption

    Författare :Fredrik Kartberg; Göteborgs universitet; []
    Nyckelord :ARF1; COPI; ARFGAP; vesicle; fusion; diffusion;

    Sammanfattning : In the secretory pathway, movement of proteins between compartments occurs through small (50-100 nm) vesicles. The coat of COPI vesicles is composed the small GTPase ARF1 and the large coatomer complex. In the secretory pathway, these vesicles mediate Golgi-to-ER and intra-Golgi transport. LÄS MER