Sökning: "propofol"

Visar resultat 16 - 20 av 44 avhandlingar innehållade ordet propofol.

1. 16. Cellular mechanisms of anaesthetic agents

   Författare :Karin Björnström Karlsson; Bertil Fredholm; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Anaesthesia is given to approximate 5% of the Swedish population annually, with the great advantage of painless surgery, but it also has side effects such as depression of blood pressure that might give a heart infarction. Exactly how anaesthetic agents cause anaesthesia is poorly known. LÄS MER

3. 17. Aspects of intravenous anaesthesia

   Författare :Jan Gelberg; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Background:Developments in anaesthesia during the recent decades include new drugs with limited unwanted side effects and the need for anaesthesia in new interventions, together with new groups of patients that in the past were considered to be beyond help. Aims:Study I: To determine the bolus dose of remifentanil that depresses the ventilatory drive as deeply as 1 µg/kg of fentanyl. LÄS MER

4. 18. A novel drug and device in anesthesia : with focus on breathing and upper airway physiology

   Författare :Åse Lodenius; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Anesthesia-related airway complications are associated with hypoxia due to inability to secure or maintain the airway with subsequent insufficient ventilation and gas exchange. This thesis has explored the impact on airway integrity and respiratory regulation of two anesthetic compounds frequently used for sedation and a novel principle for oxygenation in patients at risk of hypoxia, in order to further improve patient safety during sedation and induction of anesthesia. LÄS MER

5. 19. Pharmacometric Models in Anesthesia and Analgesia

   Författare :Marcus Björnsson; Ulrika Simonsson; Mats Karlsson; Leonid Gibiansky; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; Anesthesia; Analgesia; Dropout; NONMEM; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

   Sammanfattning : Modeling is a valuable tool in drug development, to support decision making, improving study design, and aid in regulatory approval and labeling. This thesis describes the development of pharmacometric models for drugs used in anesthesia and analgesia. LÄS MER

7. 20. Neurally adjusted ventilatory assist : from animal studies to clinical practice

   Författare :Francesca Campoccia Jalde; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Neurally Adjusted Ventilatory Assist;

   Sammanfattning : Patients in the Intensive Care Unit (ICU) undergoing ventilator treatment may experience asynchrony with the ventilator, which has been associated with increased need of sedation, sleep disruption, prolonged mechanical ventilation and unsuccessful weaning from the ventilator. The search for new strategies to improve patient-ventilator interaction is ongoing. LÄS MER