Sökning: "promoter"

Visar resultat 16 - 20 av 811 avhandlingar innehållade ordet promoter.

1. 16. B cell activation in vitro: thymus-dependent immune responses and bacterial cell surface proteins

   Författare :Karol Axcrona; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nuclear transport; bacterial Ig-binding proteins; CD40L promoter; CD21; Ig; B lymphocyte activation in vitro; CD40; Immunology; serology; transplantation; Immunologi; serologi;

   Sammanfattning : In this thesis aspects of peripheral B lymphocyte differentiation were studied. Through in vitro experiments, B lymphocyte activation was assessed. B lymphocytes express immunoglobulin (Ig) specific for a certain antigen on the cell surface, and when surface Ig is crosslinked by an antigen, the cell is activated. LÄS MER

3. 17. Regulation of artemisinin biosynthesis in Artemisia annua L

   Författare :Ke Yang; Peter E. Brodelius; Åke Strid; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; regulation of artemisinin biosynthesis; Artemisia annua transcription factors; AaMYB1; wounding treatment; promoter cloning; GC-MS; qPCR; Biokemi; Biochemistry; Mikrobiologi; Microbiology;

   Sammanfattning : Artemisinin and its derivatives are the most powerful medicines against malaria. However,the low annual yield of artemisinin from industry restricts the usage of this effective drug inendemic areas such as Africa. Nowadays the artemisinin industry mainly depends onextractions from Artemisia annua L. LÄS MER

4. 18. Novel Synthetic Biology Tools for Metabolic Engineering of Saccharomyces cerevisiae

   Författare :Siavash Partow; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yeast promoter; MVA pathway; Metabolic engineering; Multi-copy plasmid.; Synthetic biology; S. cerevisiae; MEP pathway;

   Sammanfattning : The most well characterized eukaryote model organism Saccharomyces cerevisiae is not only preferred as a microbial cell factory for synthesis of industrial products, e.g. bioethanol, but this eukaryote host system is also defined as a robust scaffold for commercial production of diverse chemicals e.g. LÄS MER

5. 19. Molecular mechanism of cell regulatory properties of vitamin D analogues in human cancer cell lines

   Författare :Carina Danielsson; Uppsala universitet; []
   Nyckelord :Medical sciences; vitamin D analogues; retinoids; cancer cell lines; promoter selectivity; cellregulatory properties; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

   Sammanfattning : The active form of vitamin D, 1α,25-dihydroxyvitamin D3, is a potent modulator of the induction of differentiation and inhibition of cell growth in both malignant and normal cells. Vitamin D and its analogues exert their effects through a transcription factor, the nuclear vitamin D receptor (VDR). LÄS MER

7. 20. Some New Methods in Sialic Acid Chemistry

   Författare :Teddy Ercegovic; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; thioglycoside promoter; ganglioside; Tumor-associated antigen; lactam; lactone; sialic acid; N-acetylneuraminic acid; Neu5Ac; sialyl donor; auxiliary group; 3- S -phenylthio; bis-sialic acid lactam; 3- S -phenylseleno; silver trifluoromethanesulfonate; iodine monochloride; Organic chemistry; Organisk kemi;

   Sammanfattning : Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. LÄS MER