Sökning: "proliferation"

Visar resultat 11 - 15 av 1934 avhandlingar innehållade ordet proliferation.

  1. 11. Cell cycle deregulation in breast cancer subgroups and effects on proliferation, migration and tamoxifen resistance

    Författare :Sophie Lehn; Malmö Molekylär patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; subgroups; proliferation; migration; stem cells; tamoxifen; estrogen receptor;

    Sammanfattning : Breast cancer is a heterogenous disease which can be divided in subgroups of distinct biology with disparate prognosis and response to treatment. The overall aim of this thesis was to delineate subgroup specific behaviour in breast cancer cells with focus on proliferation, migration and stem-like cell activity. LÄS MER

  3. 12. The Prognostic Impact of Proliferation Markers in Breast Cancer with Emphasis on Cyclin B1 and PPH3

    Författare :Anthoula Koliadi; Marie-Louise Fjällskog; Thomas Hatschek; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proliferation; cyclin B1; Phosphorylated Histone 3; cyclin A; breast cancer; node negative; prognostic factor; luminal; Oncology; Onkologi;

    Sammanfattning : The aim of this thesis was to investigate the prognostic role of the proliferation markers cyclin B1 and Phosphorylated Histone 3 (PPH3) in breast cancer (BC).In paper I we used an experimental study design, we compared women dying early from their BC with women free from relapse more than eight years after initial diagnosis. LÄS MER

  4. 13. Study of the Proliferation, Function and Death of Insulin-Producing Beta-Cells in vitro: Role of the Transcription Factor ZBED6

    Författare :Xuan Wang; Nils Welsh; Nils Billestrup; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ZBED6; Pancreatic beta-cell; Proliferation; Insulin secretion; Apoptosis; Adhesion; Medical Science; Medicinsk vetenskap;

    Sammanfattning : A thorough understanding of beta-cell proliferation, function, death and regeneration under normal condition as well as in the progression of diabetes is crucial to the conquest of this disease. The work presented in this thesis aimed to investigate the expression and role of a novel transcription factor, Zinc finger BED domain-containing protein 6 (ZBED6), in beta-cells. LÄS MER

  5. 14. Human T lymphocyte proliferation : surface molecules and accessory signalling

    Författare :Göran Ocklind; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  7. 15. Validation of Several Nucleoside Tracers as Proliferation Markers

    Författare :Li Lu; Sven Reske; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biopharmacy; PET; cell proliferation; DNA synthesis; hydroxyurea; cimetidine; diuretic; Biofarmaci; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : Positron emission tomography (PET) is a powerful method for in vivo characterization of tumor biochemistry and clinically has been used for diagnosing and grading of malignancy. A key element in oncology is proliferation potential, a feature that is assumed to be an important indicator of tumor growth. LÄS MER