Sökning: "prognos"

Visar resultat 16 - 20 av 163 avhandlingar innehållade ordet prognos.

  1. 16. Genomic profiling of breast cancer by microarray-based technology and bioinformatics

    Författare :Johan Staaf; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Survival; Prognostic predictor; Gene Expression; ERBB2; HER2; Microarray; Copy Number Analysis; CGH; aCGH; Amplification; Gene expression analysis;

    Sammanfattning : Cancer is a genetic disease that arises when a cell acquires unlimited growth potential through a series of mutational events, which target genes essential for normal cell control and maintenance. Breast cancer is one of the most frequent malignancies in women worldwide, and it is characterized by heterogeneous tumor biology, histological subtypes, variable prognosis and variable responsiveness to treatment. LÄS MER

  3. 17. Induced hypothermia after cardiac arrest

    Författare :Niklas Nielsen; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complications; evidence; neurological outcome; survival; induced hypothermia; cardiac arrest; randomised trial; heart arrest;

    Sammanfattning : This thesis is based on studies of the clinical use of induced hypothermia as an intervention to reduce mortality and neurological impairment after cardiac arrest. After the publication of two trials indicating benefit of induced hypothermia, we developed a registry to assess outcome, possible adverse events and conduct of induced hypothermia when this intervention was implemented in a clinical population of cardiac arrest patients. LÄS MER

  4. 18. FDG-PET in Cervical Cancer - Translational Studies

    Författare :Maria Bjurberg; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cervical cancer is the second most common cancer in females. The treatment, based on clinical FIGO stage, carries a significant risk of side effects. FDG-PET enables non-invasive studies of glucose metabolism. Cancer cells show an increased glucose uptake and metabolism that can be visualised and further analysed. LÄS MER

  5. 19. Classification and Computational Methods in Gene Expression Data Analysis

    Författare :Cecilia Ritz; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatik; medicinsk informatik; Bioinformatics; medical informatics; biomathematics biometrics; missing values; leukemia; cDNA microarray data; supervised classification; breast cancer; prognostic markers; biomatematik;

    Sammanfattning : The technology of cDNA microarrays has given us the possibility to monitor the state of cells by measuring the activity of thousands of genes simultaneously. This high-throughput techniqe has in cancer research allowed exploratory studies of molecular mechanisms behind for example metastasis and response to therapy. LÄS MER

  7. 20. Characterization of the perturbed differentiation in neuroblastoma, aided by the analysis of normal sympathetic nervous system development

    Författare :Carolina Gestblom; Lund Wallenberg Neurocentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; development; TrkA; apoptosis; proliferation; sympathetic nervous system; neuronal; paraganglia; neuroblastoma; chromaffin; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Neuroblastoma is a pediatric tumor derived from cells in the sympathetic nervous system. In an attempt to explain the heterogeneous clinical behavior of neuroblastoma tumors, neuroblastomas have been characterized with regard to their degree of sympathetic differentiation. LÄS MER