Sökning: "progenitor complex"

Visar resultat 1 - 5 av 71 avhandlingar innehållade orden progenitor complex.

  1. 1. Transposable Elements in Neural Progenitor Cells

    Författare :Liana Fasching; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable Elements; TRIM28; Epigenetic Regulation; Gene Expression; Neural Progenitor Cells;

    Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER

  3. 2. Structural and functional studies of a novel Botulinum neurotoxin and of MTH1

    Författare :Linda Henriksson; Pål Stenmark; Maria Selmer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Botulinum neurotoxin; botulism; cancer; gene cluster; molecular structures; MTH1; NTNH; oxidised nucleotides; progenitor complex; protein expression; protein purification; X-ray crystallography; Biochemistry; biokemi;

    Sammanfattning : X-ray crystallography visualizes the three dimensional molecular structures of proteins at atomic resolution. Seeing the molecular structure of a biomedically interesting protein enables a higher understanding of its function. LÄS MER

  4. 3. Derivation, propagation and differentiation of human stem and progenitor cells

    Författare :Mathilda Zetterström Axell; Göteborgs universitet; []
    Nyckelord :Human embryonic stem cells; neural progenitor cells; stem cells; differentiation; propagation; migration; cell culturing; rostral migratory stream; electrospun scaffolds;

    Sammanfattning : Neuronal loss is a common feature of many neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease and traumatic brain injury. Human embryonic stem cells (hESCs) and hESC-derived neural progenitors (NPs) may provide a number of new ways for studying and treating diseases and injuries in the brain. LÄS MER

  5. 4. Novel skeletal stem and progenitor cells and their regulation

    Författare :Baoyi Zhou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development of bone and cartilage, which provide the framework of the skeletal system, is complex. In this context stem and progenitor cells play a crucial role by producing differentiated cells. Hormones are important regulators of this process, with growth hormone (GH) acting as the major endocrine regulator of longitudinal bone growth. LÄS MER

  7. 5. New neurons and astrocytes in the adult brain. Studies on adult rat neural progenitors in vivo and in vitro with special reference to the effects of IGF-I and CNTF regarding proliferation and lineage determination

    Författare :Maria A I Åberg; Göteborgs universitet; []
    Nyckelord :Brain; hippocampus; rat; neurogenesis; progenitor cell; stem cell; ciliary neurotrophic factor; insulin-like growth factor-I; PI3-K; MAPK.;

    Sammanfattning : The hippocampal dentate gyrus in several species, including man, continues to produce new neurons and glial cells in adulthood. The generation of new neurons and glial cells in the adult hippocampus is under strict regulation. Two major events of significance for cell genesis from progenitor cells are proliferation and lineage determination. LÄS MER