Sökning: "progenitor cells"

Visar resultat 1 - 5 av 417 avhandlingar innehållade orden progenitor cells.

1. 1. Characterization of Retinal Progenitor Cells : Focus on Proliferation and the GABAA Receptor System

   Författare :Henrik Ring; Finn Hallböök; Per Söderberg; Andras Simon; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regeneration; Proliferation; Neurotransmitters; Müller cells; Differentiation; Retinal repair; Neurogenesis; Medical Science; Medicinsk vetenskap;

   Sammanfattning : One strategy to repair an injured or degenerated retina is to stimulate the replacement of damaged or dead neurons with cells derived from endogenous stem- or progenitor cells. A successful strategy requires knowledge about how the proliferation and differentiation of the endogenous cells are regulated. LÄS MER

3. 2. Derivation, propagation and differentiation of human stem and progenitor cells

   Författare :Mathilda Zetterström Axell; Göteborgs universitet; []
   Nyckelord :Human embryonic stem cells; neural progenitor cells; stem cells; differentiation; propagation; migration; cell culturing; rostral migratory stream; electrospun scaffolds;

   Sammanfattning : Neuronal loss is a common feature of many neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease and traumatic brain injury. Human embryonic stem cells (hESCs) and hESC-derived neural progenitors (NPs) may provide a number of new ways for studying and treating diseases and injuries in the brain. LÄS MER

4. 3. Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation

   Författare :Nina Rogelius; CNS Genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; subventricular zone; Islet1; Neurogenin2; respecification; in vivo.; transcription factors; neurogenesis; Progenitor cells; stem cells;

   Sammanfattning : New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. LÄS MER

5. 4. Transposable Elements in Neural Progenitor Cells

   Författare :Liana Fasching; Molekylär neurogenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable Elements; TRIM28; Epigenetic Regulation; Gene Expression; Neural Progenitor Cells;

   Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER

7. 5. Auxiliary Cells for the Vascularization and Function of Endogenous and Transplanted Islets of Langerhans

   Författare :Liza Grapensparr; Per-Ola Carlsson; Leif Jansson; Mia Phillipson; Aileen King; Uppsala universitet; []
   Nyckelord :Islets of Langerhans; beta cells; diabetes; transplantation; vascularization; Schwann cells; endothelial progenitor cells; neural crest stem cells; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Type 1 diabetes develops through the progressive destruction of the insulin-producing beta-cells. Regeneration or replacement of beta-cells is therefore needed to restore normal glucose homeostasis. Presently, normoglycemia can be achieved by the transplantation of whole pancreas or isolated islets of Langerhans. LÄS MER