Sökning: "procoagulant"

Visar resultat 21 - 25 av 35 avhandlingar innehållade ordet procoagulant.

  1. 21. Coagulation, fibrinolysis and inflammation in open surgery for infrarenal abdominal aortic aneurysm

    Författare :Anders Holmberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Abdominal aortic aneurysm; blood coagulation; fibrinolysis; cytokines; leucocytes; flow cytometry; chemotaxis; lactoferrin; myeloperoxidase; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Elective repair of infrarenal abdominal aortic aneurysm (AAA) carries a mortality of 4-8% and there is a substantial incidence of serious non-lethal complications. During surgery there is a situation of relative ischaemia and subsequent reperfusion of the lower part of the body. LÄS MER

  3. 22. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection

    Författare :Sofia Nordling; Peetra Magnusson; Paul Kubes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial cells; Thrombosis; Innate immunity; Immunothrombosis; Thromboinflammation; Immunologi; Immunology;

    Sammanfattning : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. LÄS MER

  4. 23. Tissue Factor and CD40 Ligand : Markers for the Interplay of Coagulation and Inflammation in the Acute Coronary Syndrome

    Författare :Anders Mälarstig; Agneta Siegbahn; Lars Wallentin; Taavo Tenno; Fiona Green; Uppsala universitet; []
    Nyckelord :Molecular medicine; tissue factor; CD40 ligand; gene expression; single nucleotide polymorphism; acute coronary syndrome; myocardial infarction; coagulation; inflammation; Molekylärmedicin;

    Sammanfattning : BACKGROUND: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. CD40 ligand is another membrane molecule, which ligates to cell types associated with atherosclerotic plaques thereby mediating intraplaque inflammation and weakening of the fibrous cap. LÄS MER

  5. 24. Thrombosis in Children

    Författare :Olof Rask; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Child; Estradiol; Heart Defects; Congenital; Hemostasis; Protein C Inhibitor; Risk factors; Thrombophilia; Thromboembolism; Autoantibodies; Adolescent;

    Sammanfattning : Aims: The general objective was to further elucidate thromboembolic disease in children and thereby help improve the care of these patients. More specific aims were as follows: to determine what children are affected by thrombosis; to discern any gender or age differences related to thrombosis; to identify prothrombotic risk factors; to ascertain whether autoantibodies against coagulation proteins constitute a risk factor for childhood thrombosis; to study girls receiving estrogen treatment with regard to induced hemostatic changes and efficacy of the therapy; to investigate long-term effects on the hemostatic system in children subjected to heart surgery. LÄS MER

  7. 25. Anticoagulant protein C--structural and functional studies

    Författare :Lei Shen; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzymology; Proteins; Klinisk kemi; Clinical chemistry; serpins; membrane binding; factor V; protein C; protein S; Proteiner; enzymologi;

    Sammanfattning : Anticoagulant protein C is a vitamin K-dependent factor circulating in plasma as a zymogen of a serine protease. It is converted to its active form (APC) by the thrombin-thrombomodulin complex on the surface of endothelial cells. APC inhibits the generation of thrombin by selective proteolytic inactivation procoagulant factors Va and VIIIa. LÄS MER