Sökning: "pristane induced arthritis"
Visar resultat 11 - 14 av 14 avhandlingar innehållade orden pristane induced arthritis.
11. Genetic and immunological studies of experimental arthritis, with emphasis on a novel C-type lectin receptor gene complex
Sammanfattning : Rheumatoid Arthritis (RA) is a chronic, systemic autoimmune syndrome primarily affecting peripheral joints. The etiology of RA is largely unknown but complex interactions between genetic and environmental factors contribute to the disease. Arthritis models more or less resembling RA are used to search for clues. LÄS MER
12. Functional and genetic analyses of the MHC and its impact on autoimmunity in the rat
Sammanfattning : The major histocompatibility complex (MHC) is an allele-rich and exceptionally gene dense region on human chromosome 6. Over 40% of the genes in this region have immune-related functions, including genes encoding MHCI and MHCII molecules. These molecules, which are found in nearly all vertebrates, present antigenic peptides to CD4 and CD8 T cells. LÄS MER
13. Genetic studies of complex autoimmune disease
Sammanfattning : In complex autoimmune diseases, there are both genetic and environmental factors that influence our immune system and contribute to the development of disease. The pathways, interactions and mode of inheritance are difficult to unravel, and many discoveries are yet to be done. LÄS MER
14. Genetic regulation of autoimmune neuroinflammation
Sammanfattning : Multiple sclerosis (MS) is a complex disease characterized by inflammation and demyelination in the central nervous system (CNS), causing neurological deficits. Although there is an increased familial aggregation rate and evidence for a genetic influence on disease susceptibility, environmental factors are also of importance. LÄS MER
