Sökning: "primary progressive multiple sclerosis"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden primary progressive multiple sclerosis.

1. 1. Diagnostic, prognostic and management aspects of different types of multiple sclerosis

   Författare :Petra Nilsson; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; optic neuritis; multiple sclerosis; cerebrospinal fluid; magnetic resonance imaging; prognosis; cognition; diagnosis; primary progressive multiple sclerosis; tumefactive MS; craniectomy;

   Sammanfattning : Background: The aim in the thesis is to study diagnostic issues, clinical features, therapy, and prognosis in selected demyelinative disorders of the nervous system: optic neuritis (ON), primary progressive MS (PPMS), and tumefactive MS (a very rare acute demyelinating disorder). Methods: From an initial cohort of 110 patients with ON collected 19 to 31 years ago, a new follow-up survey was conducted in 50 patients who on a previous follow up had not developed MS. LÄS MER

3. 2. Innate immunity in progressive multiple sclerosis

   Författare :Shahin Aeinehband; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Multiple sclerosis is (MS) is a chronic inflammatory autoimmune disease of central nervous system (CNS) leading to demyelination, axonal damage and neurological handicap, often affecting young adults. A majority of patients with MS initiate their disease with clinical bouts and relapses, but with time convert to a progressive course with dampened signs of CNS inflammation but increasing neurological deficits. LÄS MER

4. 3. Immunogenetic studies of multiple sclerosis

   Författare :Arturs Ligers; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Multiple sclerosis; CTLA-4; HLA-A2; HLA-A3; HLA-DRB1*15; HLA-DRB1*;

   Sammanfattning : Multiple sclerosis (MS) is an inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS). Several genetic factors are likely to be of importance for MS rather than one factor. LÄS MER

5. 4. Work ability in multiple sclerosis : the impact of immunomodulating treatments and adjusted working conditions

   Författare :Anne Wickström; Anders Svenningsson; Magnus Vrethem; Charlotte Dahle; Lars Forsgen; Fredrikson Sten; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Background Multiple sclerosis (MS) is a chronic inflammatory, demyelinating disease affecting the central nervous system (CNS) and is considered to be of autoimmune origin. The prevalence in Sweden is estimated to be about 1 in 500. LÄS MER

7. 5. Epidemiological and radiological aspects of multiple sclerosis

   Författare :Anne-Marie Landtblom; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The first aim of this investigation was to analyse possible risk factors for multiple sclerosis (MS) with focus on animal contacts and occupational exposures, especially to organic solvents. Another aim was to search for specific features in solvent-exposed MS patients mainly by the radiological techniques magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy ( 1 H MRS) and also by cerebrospinal fluid (CSF) analysis along with a disability scoring. LÄS MER