Sökning: "primary afferent"
Visar resultat 1 - 5 av 28 avhandlingar innehållade orden primary afferent.
1. A sensory role for the cruciate ligaments : regulation of joint stability via reflexes onto the γ-muscle-spindle system
Sammanfattning : Reflex effects evoked by graded electrical stimulation of the posterior articular nerves (PAN) of the ipsi- and contralateral knee joints were investigated using both micro-electrode recordings from 7 - motoneurones and recordings from single muscle muscle spindle afferents. Spindle afferent responses were also recorded using natural stimulation of different types of receptors, to elucidate if the articular reflexes onto the y -motoneurones were potent enough to significantly alter the muscle spindle afferent activity. LÄS MER
2. Monoaminergic modulation in spinal reflex pathways from group I afferents
Sammanfattning : Serotonin and noradrenaline are known to play an important part in modulation of spinal neuronal networks. Group I muscle afferents mediate information on dynamic changes of muscle length and tension, and modulation of actions from these afferents could be of importance for the execution of movements. LÄS MER
3. A pathway for pleasant touch: linking peripheral receptors to central processing and hedonic experience
Sammanfattning : This thesis investigates the mechanisms underpinning pleasant touch, describes a pathway from peripheral nerve endings in the skin to the insular cortex, and relates these findings to the subjective hedonic experience of touch. In Paper I, the relationship between primary afferent encoding and perception of pleasantness was investigated by combining microneurography recordings from human mechanoreceptors with psychophysical measurements during soft brush stroking at 6 different velocities between 0. LÄS MER
4. Structure and function of trigeminal primary sensory neurons after peripheral nerve injury
Sammanfattning : Iatrogenic injuries to branches of the trigeminal nerve are common during surgical procedures in the jaws and teeth, and as the repercussion of facial fractures or certain pathologies. A portion of these patients are left with disturbed sensory functions, and some with unpleasant abnormal sensations, including pain. LÄS MER
5. Neuronal tracers for fine caliber spinal primary afferents and their response to peripheral nerve injury
Sammanfattning : The isolectin B4 from Griffonia simplicifolia I (B4) and soybean agglutinin from the plant Glycine max (SBA), have been shown to bind to rat small-diameter dorsal root ganglion (DRG) neurons, and to fibers and presumed terminals in laminae I-II of the spinal cord dorsal horn. In the present thesis, these lectins and/or their horseradish peroxidase (HRP) conjugates, have been investigated in the rat with regard to their usefulness as selective neuronal markers of and axonally transported tracers for somatic and/or visceral spinal primary afferents with fine caliber, including unmyelinated, axons. LÄS MER
