Sökning: "preneoplastic lesion"

Hittade 1 avhandling innehållade orden preneoplastic lesion.

1. 1. Studies on DNA adducts and carcinogenesis with 2-nitrofluorene as a model substance

   Författare :Xian-Shu Cui; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :2-nitrofluorene; carcinogens; DNA adducts; preneoplastic lesion; tumor;

   Sammanfattning : A number of carcinogens or their electrophilic intermediates are able to bind covalently to DNA, forming DNA adducts. DNA adducts may cause gene mutations if they are misrepaired or remain unrepaired before DNA replication occurs. DNA adduct formation is believed to be the initial step of chemical carcinogenesis. LÄS MER