Sökning: "predictive biomarker"

Visar resultat 6 - 10 av 114 avhandlingar innehållade orden predictive biomarker.

  1. 6. Population-based studies of atrial fibrillation and ischemic stroke

    Författare :John Berntsson; Kardiovaskulär forskning - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; Ischemic stroke; Biomarker; Stroke; Natriuretic peptides; Vascular endothelial growth factor; Epidemiology; Atrial Fibrillation; Stroke; Ischemic stroke; Natriuretic peptides; Vascular endothelial growth factor; Epidemiology;

    Sammanfattning : AbstractBackground: Atrial fibrillation (AF) is a major risk factor for ischemic stroke and the most common cause of cardioembolic stroke. Early detection of AF and AF subjects at high risk for stroke is therefore important. LÄS MER

  3. 7. Lifestyle and glycaemic control before and after the onset of type 2 diabetes

    Författare :Robert Koivula; Genetisk och molekylär epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Prediabetes; Obesity; Beta-cell Function; Insulin Sensitivity; Physical Activity; Exercise; Diet; Lifestyle; Ectopic Fat; Genetic Epidemiology; Genetic Risk; Biomarker; Precision Medicine;

    Sammanfattning : Type 2 diabetes (T2D) is a complex disease with widespread physiological insults to the regulation of metabolic homeostasis, above all glycaemic regulation. The pathogenesis of T2D and its progression is broadly understood to be through a gradual decrease in peripheral insulin sensitivity, a compensatory rise in insulin secretion, and a gradual decline in beta-cell function, resulting in glycaemic dysregulation and eventual T2D. LÄS MER

  4. 8. Biomarkers In Brain Tumors With Focus On Glioblastoma

    Författare :Malgorzata Lysiak; Peter Söderkvist; Annika Malmström; Olle Stål; Mattias Belting; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; MGMT; Biomarker; Sex differences; Androgen receptor; Loss of chromosome Y;

    Sammanfattning : The primary brain tumors, gliomas, are not very common but they are deadly. Each year in Sweden around 500 patients will be diagnosed with a glioma and unfortunately most of them will have the most aggressive type, glioblastoma (GBM). Median survival, even if treated, is poor (14-17 months). LÄS MER

  5. 9. Biomarkers of vascular function and structure in young healthy adults

    Författare :Paul Pettersson-Pablo; Anita Hurtig-Wennlöf; Torbjörn Nilsson; Lars Breimer; Anders Larsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; vascular function; vascular structure; body composition; age; inflammation; clinical chemistry; biomarker;

    Sammanfattning : Atherosclerosis is a disease affecting the blood vessels in the body. Its pathophysiologic mechanisms involve infiltration of the vessel walls by fatty matter and immune cells. This process is slow, starting in childhood but typically not manifesting as symptomatic disease until late adulthood (after 60 years of age). LÄS MER

  7. 10. Predictive biomarkers in rheumatoid arthritis

    Författare :Karen Hambardzumyan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Being a very heterogeneous disease, rheumatoid arthritis (RA) is challenging for treatment. On a group level, some therapy options might be superior compared with others, however, this does not mutually exclude the less effective option to be more suitable for some patients, if the superior therapy option does not help. LÄS MER