Sökning: "precision medicine"

Visar resultat 11 - 15 av 247 avhandlingar innehållade orden precision medicine.

  1. 11. Precision medicine and targeted therapy : Turning the tables on cancer

    Författare :Anja Mortensen; Marika Nestor; Gregory Adams; Uppsala universitet; []
    Nyckelord :p53 cancers; PM2; radiosensitization; radio-immunotherapy; MDM2 X inhibition; combination therapy; targeted radionuclide therapy; CD44v6; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Sammanfattning : An extended understanding of the molecular characteristics of cancer has led to a revolution within the field of precision medicine. This thesis explores the utilization of two targets for precision medicine, namely, CD44v6 and murine double-minute 2 and X (MDM2/X). LÄS MER

  3. 12. The Voice of the Patient

    Författare :Hampus Kiotseridis; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rhinitis; asthma; Patient-reported outcome; health-related quality of life; Children; asthma control; pollen warning; grass pollen allergy;

    Sammanfattning : Allergic diseases, which constitute a global health problem, have been defined as one of the epidemics of the twenty-first century. Since there are no cures for allergic diseases today, the goal of treatment is to get the disease under control so that the patient can live a normal life with optimal chances of development. LÄS MER

  4. 13. Uncemented Total Hip Arthroplasty : Aspects on Bone Biology, Implant Fixation, Periprosthetic Bone Remodeling, Bone Mineral Density and Effects of Denosumab

    Författare :Andreas Nyström; Hans Mallmin; Nils Hailer; Gösta Ullmark; Jens Sörensen; Arkan Sayed-Noor; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; THA; F-PET; Denosumab; CTMA;

    Sammanfattning : Uncemented total hip arthroplasty (THA) is associated with loss of periprosthetic bone mineral density (BMD). The collum femoris preserving (CFP) stem lost 28% of proximal BMD at 2 years. LÄS MER

  5. 14. Quantification Methods for Clinical Studies in Nuclear Medicine - Applications in AMS, PET/CT and SPECT/CT

    Författare :Marie Sydoff; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear Medicine; AMS; PET CT; SPECT CT; dosimetry; internal dosimetry; quantification; activity quantification; volume delineation; radiation; biokinetics; pharmacokinetics; biodistribution;

    Sammanfattning : An essential part of the development of new radiopharmaceuticals for use in diagnostic nuclear medicine is the determination of its biokinetic properties. The uptake and turn-over of the radiopharmaceutical in the source organs is of great interest since this could determine whether the radiopharmaceutical would be suitable for clinical use or not. LÄS MER

  7. 15. Nutrition and energy expenditure in women with chronic obstructive pulmonary disease

    Författare :Nighat Farooqi; Thomas Sandström; Frode Slinde; Lena Håglin; Tommy Cederholm; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy expenditure and women; Women and COPD; Nutrition and women; lungmedicin; Lung Medicine;

    Sammanfattning : AimThe overall objective of this thesis was to increase the knowledge and validate methods for assessment of total daily energy expenditure (TEE), energy requirement and energy intake (EI) in women with COPD. We also investigated the relationship of BMI with clinical characteristics of COPD in a population-based study. LÄS MER