Sökning: "posterior fossa"

Hittade 3 avhandlingar innehållade orden posterior fossa.

  1. 1. Medical, cognitive and motor outcome after treatment of pilocytic astrocytoma in the posterior fossa in childhood

    Författare :Ingela Kristiansen; Per Frisk; B Strömberg; Klas Blomgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood; CNS tumour; pilocytic astrocytoma; posterior fossa; long-term outcome; cognition; language; motor performance; learning difficulties; Pediatrik; Pediatrics;

    Sammanfattning : Introduction: Pilocytic astrocytoma is the most common brain tumour in childhood. The aim of the studies was to investigate late medical, cognitive and motor complications in patients treated in childhood for pilocytic astrocytoma in the posterior fossa. LÄS MER

  3. 2. Mechanisms of Medulloblastoma Dissemination and Novel Targeted Therapies

    Författare :Sara Bolin; Fredrik Swartling; Martine F. Roussel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medulloblastoma; Recurrence; MYC; SOX9; FBW7; Treatment; BET bromodomains; Cyclin-dependent kinases; Oncology; Onkologi;

    Sammanfattning : Medulloblastomas are the most frequent malignant childhood brain tumors, arising in the posterior fossa of children. The overall 5-year survival is 70%, although children often suffer severe long-term side effects from standard medical care. LÄS MER

  4. 3. MYC-driven Medulloblastoma : New Targeted Therapies and Mechanisms of Recurrence

    Författare :Anna Borgenvik; Fredrik J. Swartling; Lars-Gunnar Larsson; Sonja Hutter; Pratiti (Mimi) Bandopadhayay; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medulloblastoma; Pediatric cancer; Recurrence; MYC; MYCN; SOX9; Treatment; Bet bromodomains; Cyclin-dependent kinases; Oncology; Onkologi; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Medulloblastoma is the most common malignant brain tumor of childhood. It arises in the posterior fossa but presents with distinct histological and molecular features. Hence, medulloblastoma is divided into four molecular subgroups, WNT, SHH, Group 3, and Group 4. LÄS MER