Sökning: "population genetics"
Visar resultat 11 - 15 av 469 avhandlingar innehållade orden population genetics.
11. Following the herd : Population genetics of European sheep in time and space
Sammanfattning : Sheep, which were domesticated in the Fertile Crescent about 10,000-12,000 years ago, have been a key resource for human populations ever since. We, however, know little about how they were domesticated, and what happened to them after their initial expansion from their domestication area into all corners of Eurasia and later Africa and the Americas. LÄS MER
12. Population genetic history and patterns of admixture : Examples from northeastern and southern Africa
Sammanfattning : The origin of humans lies in Africa, as has been shown by archaeology, paleontology and genetics. Here, we can find the largest genetic diversity and the deepest split among human populations. African genetic diversity has been shaped by a long and complex history. LÄS MER
13. Exploring the Genetics of SLE with Linkage and Association Analysis
Sammanfattning : The aim with this thesis has been to identify genes involved in the pathogenesis of Systemic Lupus Erythematosus (SLE). SLE is a systemic autoimmune disorder, most likely caused by both several genetic and environmental factors. LÄS MER
14. Surviving the ratchet : Modelling deleterious mutations in asexual populations
Sammanfattning : One of the most unforgiving processes in nature is that of Muller's ratchet, a seemingly irreversible accumulation of deleterious mutations that all organisms have to deal with or face extinction. The most obvious way to avoid fitness collapse is recombination, though asexual populations usually do not have the luxury of recombining freely. LÄS MER
15. Immunity & the butterfly : A functional genomic study of natural variation in immunity
Sammanfattning : Butterflies are ubiquitous and abundant, occurring in a wide variety of environments that contain diverse microbial communities with varied pathogenic pressures. These pathogens and parasites present a constant threat to organisms, and have led to the evolution of complex and intricate immune responses. LÄS MER
