Sökning: "population based"

Visar resultat 16 - 20 av 3797 avhandlingar innehållade orden population based.

1. 16. Risk Factors for Stroke in Adult Men : A Population-based Study

   Författare :Bernice Wiberg; Lars Lind; Johan Sundström; Björn Zethelius; Peter Appelros; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; risk factor; stroke; TIA; lipoproteins; fatty acids; insulin resistance; proinsulin; clamp; cognitive function; epidemiology; Trail Making Test; stroke mortality; dependency; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi; Medicinsk vetenskap; Medical Science;

   Sammanfattning : In the last decades our knowledge concerning cardiovascular risk factors has grown rapidly through results from longitudinal studies. However, despite new treatment, in Western countries coronary heart disease remains the leading cause of death and stroke is still the leading cause of severe disability. LÄS MER

3. 17. The biology of cognitive decline and reduced survival in Parkinson disease : prognostic factors in a population-based cohort

   Författare :David C Bäckström; Lars Forsgren; Jan Linder; Niklas Lenfeldt; Jan Aasly; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson disease; multiple system atrophy; progressive supranuclear palsy; natural history; cognitive impairment; dementia; predictors of mortality; cerebrospinal fluid biomarkers; prospective; population-based; Neurology; neurologi;

   Sammanfattning : Parkinson disease (PD) is a progressive neurodegenerative disease that affects about 1% of the population over 60 years. The cardinal symptoms are motor disabilities but cognitive decline is also common. About 50% of all persons with PD develop dementia within 10 years after disease onset. LÄS MER

4. 18. Population-based studies in Myelodysplastic syndromes : Prognostic scores, socioeconomic status, and therapy-related disease

   Författare :Daniel Moreno Berggren; Elisabeth Ejerblad; Sören Lehmann; Martin Jädersten; David Bowen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myelodysplastic syndromes; Chronic myelomonocytic leukaemia; Prognostication; Comorbidity; Therapy-related disease; Real-world data; Population-based studies; Medicinsk vetenskap; Medical Science;

   Sammanfattning : The aim of this thesis was to expand the epidemiological knowledge of the haematological malignancy MDS and the related condition chronic myelomonocytic leukaemia (CMML). Using nationwide registers, the papers in this thesis address aspects of prognostication, comorbidity, socioeconomic status, and therapy-related disease, using a population-based approach. LÄS MER

5. 19. Dose Adaptation Based on Pharmacometric Models

   Författare :Johan Wallin; Mats Karlsson; Lena Friberg; Maria Garrido; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biopharmacy; Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

   Sammanfattning : Many drugs exhibit major variability in both pharmacokinetic (PK) and pharmacodynamic (PD) parameters that prevents the use of the same dose for all patients. Variability can occur both between patients (IIV) as well as within patients over the course of time (IOV). LÄS MER

7. 20. Population viability analysis for plants : practical recommendations and applications

   Författare :Satu Ramula; Kari Lehtilä; Patrik Dinnétz; Esa Ranta; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; demography; matrix population models; population viability analysis; population growth rate; stochastic models; Biology; Biologi;

   Sammanfattning : Population viability analysis (PVA) is commonly used in conservation biology to predict population viability in terms of population growth rate and risk of extinction. However, large data requirements limit the use of PVA for many rare and threatened species. LÄS MER