Sökning: "polymicrobial infections"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden polymicrobial infections.

  1. 1. Bacterial Outer Membrane Vesicles. Mediators of virulence and antibiotic resistance

    Författare :Viveka Schaar; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; Moraxella catarrhalis; epithelial cells; beta-lactamase; non-typeable Haemophilus influenzae; outer membrane vesicles; polymicrobial infections; UspA1;

    Sammanfattning : Outer membrane vesicles (OMV) have the size of nanoparticles and are released from the outer membrane of most Gram-negative bacteria. The OMV reflect the composition of the bacterial outer membrane, including lipids and virulence factors specific for the pathogen, and are involved in pathogenesis and bacterial survival. LÄS MER

  3. 2. Periprosthetic Joint Infections. Clinical and Epidemiological Aspects

    Författare :Olof Thompson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prosthetic joint infection; arthroplasty; Streptococcus; Enterococcus; register; mortality;

    Sammanfattning : Periprostheteic joint infection (PJI) is a rare complication of arthroplasty with severe consequences for the affected patients. PJI most often necessitates additional surgery and prolonged courses of antibiotic treatment, leading to worse functional results and increased societal costs. LÄS MER

  4. 3. Rapid microbiological diagnosis of infections in sterile body fluids including blood

    Författare :Osman Altun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Infections of normally sterile body fluids (SBF) including blood, cerebrospinal-, pleural-, peritoneal-, pericardial and synovial fluid are critical and require early diagnosis and rapid initiation of appropriate antimicrobial therapy. With the advanced and invasive care of modern medicine, infections of SBF are increasing worldwide. LÄS MER

  5. 4. Bacterial physiology and its role in antibiotic refractoriness

    Författare :Spyridon Gkotzis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The pathological outcome of a bacterial infection depends on the interplay among the host’s innate defenses, the virulence arsenal of the pathogen and antibiotic treatment strategies. Understanding this interplay will provide mechanistic insights on antibiotic pharmacodynamics and bacterial pathogenesis, and set the stage for the development of novel therapeutic interventions. LÄS MER

  7. 5. SIGNALING MECHANISMS IN SEPSIS-INDUCED IMMUNE DYSFUNCTION

    Författare :Zirak Hasan; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; neutrophil; lung; chemokines; infection; T-cells; CD44; Rho-kinase; isoprenylation;

    Sammanfattning : Sepsis and subsequent organ failure remain the major cause of mortality in intensive care units in spite of significant research efforts. The lung is the most vulnerable organ affected by early hyper-inflammatory immune response in septic patients. LÄS MER