Sökning: "poly"

Visar resultat 6 - 10 av 740 avhandlingar innehållade ordet poly.

  1. 6. Poly-and oligothiophenes : Optical probes for multimodal fluorescent assessment of biological processes

    Författare :Karin Magnusson; Peter Nilsson; Per Hammarström; Thomas Borén; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : One interesting class of molecules in the research field of imaging biological processes is luminescent conjugated polythiophenes, LCPs. These fluorescent probes have a flexible backbone consisting of repetitive thiophene units. LÄS MER

  3. 7. Poly(A)-specific Ribonuclease (PARN) : Structural and Functional Studies of Poly(A) Recognition and Degradation

    Författare :Niklas Henriksson; Anders Virtanen; Marvin Wickens; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Molecular Biotechnology; Molekylär bioteknik;

    Sammanfattning : Regulation of mRNA degradation is a powerful way for the cell to regulate gene expression. A critical step in eukaryotic mRNA degradation is the removal of the poly(A) tail at the 3'-end of the mRNA. LÄS MER

  4. 8. Bioresorbable copolymers with tailored properies : innovative materials för soft tissuel engineering

    Författare :Natalia Andronova; Ann-Christine Albertsson; Pieter Dijkstra; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; poly 1; 5-dioxepan-2-one ; poly ε-caprolactone ; poly L-lactide ; poly trimethylene carbonate ; triblock; network; cyclic tin alkoxide; controlled coordination-insertion ring-opening polymerization; thermoplastic elastomers; Polymer chemistry; Polymerkemi;

    Sammanfattning : The emerging need for new synthetic materials for soft tissue engineering applications encourages the search for innovative polymers having interesting properties. Ring-opening polymerization of lactones and lactides initiated by tin alkoxides has received particular attention due to the versatility of the method for building up well-defined biodegradable structures. LÄS MER

  5. 9. Functional Significance of Multiple Poly(A) Polymerases (PAPs)

    Författare :Helena Nordvarg; Claire Moore; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; poly A polymerase; PAP; phosphorylation; isoforms; alternative splicing; kinetic parameters; hyperphosphorylation; regulation; Genetik; Poly A polymeras; PAP; fosforylering; isoformer; alternativ splitsning; kinetiska parametrar; reglering; Clinical genetics; Klinisk genetik; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : 3’ end cleavage and polyadenylation are important steps in the maturation of eukaryotic mRNAs. Poly(A) polymerase (PAP), the enzyme catalysing the addition of adenosine residues, exists in multiple isoforms. In this study the functional significance of multiple poly(A) polymerases have been investigated. LÄS MER

  7. 10. Poly(A)-Specific Ribonuclease (PARN)

    Författare :Yan-Guo Ren; Eric Westhof; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Poly A -specific ribonuclease; PARN; deadenylation; processive; oligomeric; cap interacting; aminoglycoside; active site; FE2 -mediated cleavage; metal ion switch; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Degradation of the mRNA 3'-end located poly(A) tail is an important step for mRNA decay in mammalian cells. Thus, to understand mRNA decay in detail, it is important to identify the catalytic activities involved in degrading poly(A). LÄS MER