Sökning: "poly p-dioxanone"

Hittade 4 avhandlingar innehållade orden poly p-dioxanone.

  1. 1. Synthesis of Biomedical Polymers and Scaffold Design

    Författare :Therese Tyson; Ann-Christine Albertsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ring-opening polymerization; tin alkoxide initiator; stannous octoate; poly p-dioxanone ; copolymer; L-lactide; trimethylene carbonate; degradable porous scaffold; Polymer chemistry; Polymerkemi;

    Sammanfattning : This work has focused on the development of new improved synthesis methods of biodegradable aliphatic polymers and on the preparation of porous scaffolds for tissue engineering applications. The aim of the first part of the work was the synthesis of poly(p-dioxanone) (PPDX) homopolymers with high molecular weights using the cyclic tin alkoxide initiator 1-di-n-butyl-1-stanna-2,5-dioxacyclopentane. LÄS MER

  3. 2. Degradable copolymers in additive manufacturing: controlled fabrication of pliable scaffolds

    Författare :Astrid Ahlinder; Anna Finne Wistrand; T. Christian Gasser; Tiziana Fuoco; Minna Kellomäki; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Inom vävnadsregenerering är produktionen av väldefinieradematriser med en porös arkitektur av nedbrytbara polymerer av stortintresse, dessa kan nu skapas genom additiva tillverkningsprocesser. Vidadditiv tillverkning krävs ett smalt munstycke för att skapa detaljrikastrukturer och detta ställer krav på att de reologiska egenskapernaanpassat. LÄS MER

  4. 3. Engineering 3D degradable pliable scaffolds for adipose tissue regeneration : Advancing cell-material interactions by understanding the influence from thermal, chemical, mechanical properties and scaffold design

    Författare :Shubham Jain; Anna Finne-Wistrand; Kamal Mustafa; Mikael Hedenqvist; Lauren Flynn; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Degradable polymers; 3D scaffolds; adipose tissue regeneration; cell-material interaction; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : In soft tissue defects that arise due to trauma, tumor resections and complex burns, a significant loss in adipose tissue remains a considerable challenge due to the insufficient regenerative capacity of the tissue. This thesis focuses on assessing cell-material interactions between degradable 3D polymer scaffolds with different designs and adipose tissue-derived stem cells. LÄS MER

  5. 4. Synthetic Pathways to Aliphatic Polyesters and Scaffold Design

    Författare :Therese Tyson; Ann-Christine Albertsson; Elisabetta Ranucci; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Polymer chemistry; Polymerkemi;

    Sammanfattning : As the field of tissue engineering progresses, a continuous development of scaffold fabrication techniques and suitable degradable materials is required to obtain scaffolds with tunable characteristics. This thesis has focused on the development of pathways to synthesize degradable aliphatic polyesters and on the design of highly porous scaffolds from this class of materials. LÄS MER