Sökning: "poly L-lactide-co-glycolide"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden poly L-lactide-co-glycolide.

1. 1. Covalent Vapor-Phase Grafting of Degradable Polymers

   Författare :Martina Källrot; Ann-Christine Albertsson; Maria Nowokowska; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Vapor-phase grafting; covalent surface modification; functionalization; solvent-free grafting; sub-micron patterned topography; scaffolds; degradable polymers; poly L-lactide ; poly ε-caprolactone ; poly trimethylene carbonate ; poly L-lactide-co-glycolide ; poly 1; 5-dioxepan-2-one-co-L-lactide ; poly ε-caprolactone-co-L-lactide ; N-vinylpyrrolidone; maleic anhydride; acrylamide; acrylic acid; hyaluronic acid; in vitro degradation; Gasfasympning; kovalent ytmodifiering; funktionalisering; lösningsmedelsfri ympning; sub-micrometer mönstrad topografi; nedbrytbara polymerer; poly L-laktid ; poly ε-kaprolakton ; poly trimetylen karbonat ; poly L-laktid-co-glykolid ; poly 1; 5-dioxepan-2-one-co-L-laktid ; poly ε-kaprolakton-co-L-laktid N-vinylpyrrolidon; maleinsyraanhydrid; akrylamid; akrylsyra; hyaluronsyra; in vitro nedbrytning; Polymer chemistry; Polymerkemi;

   Sammanfattning : Gasfasympning är en del i den moderna strategin för optimering av den molekylära designen av biomaterial. Kovalent ytmodifiering med hydrofila vinylmonomerer och koppling med bioaktiva grupper används för att öka biokompatibiliteten och bioaktiviteten hos biomaterialen.. LÄS MER

3. 2. Poly(Lactide-co-Glycolide) in Controlled-Release Pharmaceuticals - Release Mechanisms

   Författare :Susanne Fredenberg; Avdelningen för kemiteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PLGA; Poly lactide-co-glycolide ; Release mechanism; Diffusion; Controlled Release; Degradation; Protein;

   Sammanfattning : Controlled-release formulations reduce the frequency of injections and better maintain plasma concentrations within the therapeutic window. Poly(D,L-lactide-co-glycolide) (PLG) is currently the most frequently used biodegradable polymer for this application. LÄS MER

4. 3. Synthesis and Characterization of Self-Assembling Low Molecular Weight Copolymers for Bioengineering Applications

   Författare :Jenny Fagerland; Anna Finne-Wistrand; Tim Bowden; Natalia Andronova; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cooligomers; bioengineerng applications; polymer synthesis;

   Sammanfattning : The constant need for improved biomedical materials and the interest in producing materials with similar properties to the extracellular matrix in different tissues has resulted in increasing interest in research on hydrogels. Over the last decade self-assembling copolymers have been of particular interest since they form hydrogels in response to external stimuli such as temperature. LÄS MER

5. 4. Synthesis of degradable aliphatic polyesters: strategies to tailor the polymer microstructure

   Författare :Jenny Fagerland; Anna Finne-Wistrand; David Kaplan; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Polymer synthesis; enzymatic synthesis; degradable polyesters; peptides; scaffolds; Chemical Engineering; Kemiteknik;

   Sammanfattning : Key factors for successful tissue engineering are the synthesis and design of the scaffold materials. Aliphatic polyesters have been studied and often used as scaffold materials for tissue engineering. However, their lack of biological cues and degradation under high-temperature processing (e.g. LÄS MER

7. 5. A supercritical fluids extraction process for the production of drug loaded biodegradable microparticles

   Författare :Raouf Ghaderi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

   Sammanfattning : The purpose of this thesis was to develop methods suitable for the incorporation of drug substancessuch as proteins into microparticles intended for controlled release. In particular a novel techniquefor the preparation of microparticles using supercritical fluids was investigated. LÄS MER