Sökning: "pneumococci"
Visar resultat 1 - 5 av 46 avhandlingar innehållade ordet pneumococci.
1. Unraveling the immune response in sepsis and meningitis. Diagnostic and therapeutic approaches
Sammanfattning : Severe infections continue to constitute a large burden, with high mortality and risk of sequelae. Sepsis is a dysregulated host response to an infection that causes life threatening organ damage. Meningitis is a severe infection of the brain that often leads to sepsis and death or lasting neurological damage. LÄS MER
2. Infectious and bleeding complications in patients with hematological malignancies : Studies on diagnosis and prevention
Sammanfattning : The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS).Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. LÄS MER
3. Resistant pneumococci and use of antibiotics
Sammanfattning : Pneumococcal resistance to antibiotics has become a worldwide problem. The rapid increase in frequency seems to be caused by intercontinental spread of a few resistant clones. Resistance to antibiotics in pneumococci has reduced the therapeutic arsenal for common respiratory tract infections as well as for invasive infections. LÄS MER
4. Penicillin-resistant pneumococci in Sweden : epidemiology and public health response
Sammanfattning : Since 1996, all identified cases of pneumococci with a MIC for penicillin G > 0.5 mg/L (penicillin resistant pneumococci: PRP) have been registered according to the Swedish Communicable Disease Act. LÄS MER
5. Role of HAMLET and metabolism in treatment and pathogenesis of pneumococci
Sammanfattning : Antimicrobial resistance (AMR) is one of the principle public health problems in the 21st century, threatening the available treatment strategies for bacterial infections. Here, we present a human protein-lipid complex, HAMLET (human alpha-lactalbumin made lethal to tumor cells) purified from human milk as a potential therapeutic agent which has both tumoricidal and bactericidal activity. LÄS MER