Sökning: "platinum complexes"
Visar resultat 1 - 5 av 31 avhandlingar innehållade orden platinum complexes.
1. PEPPSI-type Complexes of Palladium and Platinum: : Investigation of Properties and Applications in Catalysis
Sammanfattning : Catalysis is a powerful tool to highly efficient production of desired newchemicals by acceleration of a chemical reaction rate. Special compounds used forthis purpose are called catalysts; they induce a change in the chemicalenvironment without being consumed during the process. LÄS MER
2. Nucleic Acids as Drug Targets - Influence of Platinum Complexes on Duplex Stability and Binding Kinetics
Sammanfattning : Gaining a detailed understanding of how human cells are affected by metal-based drugs is crucial, since these drugs have shown great potential in cancer treatment. Cisplatin is used to treat many different types of cancer, e.g. testicular, ovarian, melanoma, bladder, non-small cell lung cancer, small cell lung cancer, myelomas and lymphomas. LÄS MER
3. Nucleic Acids as Drug Targets -Interactions of Platinum Complexes, Polyamines, and siRNA with DNA and RNA Models
Sammanfattning : Drugs targeting nucleic acids were studied in DNA and RNA model systems. The effects were investigated with respect to structural and thermodynamic influence, kinetics, and biological function. The drugs employed in this thesis were anticancer active platinum(II) complexes, polyamine derivatives, and siRNA. LÄS MER
4. On Thallium (III) and binuclear platinum-thallium complexes with N-donor ligands in solution and in solid
Sammanfattning : This thesis describes the synthesis, structure, equilibriaand other properties of novel thallium(III) monomeric andplatinum-bonded complexes with nitrogen donor ligandsethylenediamine, diethylenetriamine, triethylenetetramine,porphyrin, 2,2'-bipyridine and 1,10-phenanthroline in solutionand in solid.The existence of three complexes withthe general formula[Tl(en)n]3+(n = 1-3) and their overall stability constantshave been established in pyridine. LÄS MER
5. Nucleic Acids as Drugs and Drug Targets With Focus on Anticancer Active Platinum Complexes and Small Interfering RNAs
Sammanfattning : To ensure that patients receive a safe and effective treatment, it is important to understand how drugs interact with and affect molecules within a cell. Here, evaluation of platinum based drugs and their ability to interfere with nucleic acid functions is presented. LÄS MER
