Sökning: "platform strain"

Visar resultat 1 - 5 av 45 avhandlingar innehållade orden platform strain.

  1. 1. Engineering central carbon metabolism with phosphoketolase pathways in Saccharomyces cerevisiae

    Författare :John Hellgren; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; precursor supply; transcriptomics; sustainability; non-oxidative glycolysis; Carbon-conservation; metabolic engineering; platform strain; GATHCYC; proteomics;

    Sammanfattning : We need more efficient biocatalysts to make sustainable microbial production of chemicals and fuels more profitable before they can replace petroleum-based sources. Rewiring the metabolic pathways in the biocatalysts to avoid the loss of carbon as CO2 can aid in improving product yields and thereby the profitability of the process. LÄS MER

  3. 2. Microbial production of 3-hydroxypropionic acid and poly(3-hydroxypropionate): Investigation of Lactobacillus reuteri propanediol utilization pathway enzymes

    Författare :Ramin Sabet Azad; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Platform chemicals; biopolymers; 3-hydroxypropionic acid; 3-hydroxypropionaldehyde; glycerol; poly 3-hydroxypropionate ; polyhydroxyalkanoates; Escherichia coli; Lactobacillus reuteri; propanediol utilization pathway; propionaldehyde dehydrogenase; biotransformation; cofactor regeneration; NADH oxidase;

    Sammanfattning : Concerns regarding environmental issues such as greenhouse gas emissions and climate change have led to a shift within the research community and chemical and energy industry sectors for finding sustainable routes for producing fuels and chemicals from renewable resources, thereby minimizing our dependence on petroleum. The C3-chemical 3-hydroxypropionic acid has been identifed as a top candidate for the biobased chemical industry. LÄS MER

  4. 3. Improved CWM platform for modelling welding procedures and their effects on structural behaviour

    Författare :Per Lindström; Lars-Erik Svensson; Lennart Josefson; Hannu Hänninen; Högskolan Väst; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; CWM; FEM; WELD; STRESS; EPFM; Manufacturing and materials engineering; Produktions- och materialteknik;

    Sammanfattning : A welding procedure specification is the document describing how a weld joint should be constructed. Arc weld processes are characterized by transient thermal behavior, leading to rapid changes in material properties and dynamic interaction between weld and base material. LÄS MER

  5. 4. Strain- and bioprocess-design strategies to increase production of (R)-3-hydroxybutyrate by Escherichia coli

    Författare :Mónica Guevara-Martínez; Gen Larsson; Antonius J. A. van Maris; Pau Ferrer; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; E. coli; R -3-hydroxybutyrate; metabolic engineering; bioprocess design; NADPH; acetic acid; thioesterase; BAC; Bioteknologi; Biotechnology;

    Sammanfattning : Microbial bio-based processes have emerged as an alternative to replace fossil-based processes for the production of fuels and chemicals. (R)-3-hydroxybutyrate (3HB) is a medium-value chemical that has gained special attention as a precursor of antibiotics and vitamins, as a monomer for the synthesis of tailor-made polyesters and as a nutritional source for eukaryotic cells. LÄS MER

  7. 5. Characterizing phenotypes of Mycobacterium tuberculosis and exploring anti-mycobacterial compounds through high content screening

    Författare :Sadaf Kalsum; Maria Lerm; Thomas Lundbäck; Annika Jenmalm; Lena Serrander; Priscille Bordin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tuberculosis (TB), an airborne disease and one of the top 10 causes of death globally, is caused by Mycobacterium tuberculosis (Mtb). Current standard therapy for TB treatment includes multiple drugs for a period of at least 6 months. LÄS MER