Sökning: "platelets"

Visar resultat 16 - 20 av 266 avhandlingar innehållade ordet platelets.

  1. 16. Aspects of Plasminiogen Activator Inhibitor 1 in Metabolic Syndrome

    Författare :Karin Mossberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PAI-1; metabolic syndrome; obesity; type 2 diabetes; cardiovascular disease; fibrinolysis; thrombi; plasma; platelets; adipose tissue; mRNA; qPCR; reference gene;

    Sammanfattning : Plasminogen activator inhibitor 1 (PAI-1) is the main inhibitor of the fibrinolytic system and binds irreversibly to tissue-type plasminogen activator (t-PA), and thereby inhibits the protective action of t-PA against thrombus formation. Elevated levels of plasma PAI-1 is observed in subjects with type 2 diabetes (T2D) and the metabolic syndrome (MetS), which is a combination of metabolic features including obesity. LÄS MER

  3. 17. Fibrinogen, platelet and factor XIII supplementation in cardiac surgery: In vitro and in vivo studies

    Författare :Caroline Andersson Shams Hakimi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fibrinogen; platelets; factor XIII; platelet aggregation; clot formation; cardiac surgery;

    Sammanfattning : Background: There is a high risk of bleeding complications in cardiac surgery. Fibrinogen and platelet concentrates are often used to treat perioperative bleeding, but there is little information about its efficacy. LÄS MER

  4. 18. Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells

    Författare :Fredrik Sjövall; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; sepsis; severe sepsis; septic shock; platelets; mitochondria; OXPHOS; high-resolution respirometry; mitochondrial disorders; multiple organ failure; biogenesis; leukocytes; cytokines; respirometry; oxygen consumption; blood cells; temporal;

    Sammanfattning : Sepsis is a devastating disease that is caused by the host’s response to an overwhelming infectious process. As sepsis progresses, organs distant from the site of infection become affected and sepsis-induced multiple organ failure ensues. LÄS MER

  5. 19. Free oscillation rheometry in the assessment of platelet quality

    Författare :Nahreen Tynngård; Gösta Berlin; Tomas Lindahl; James AuBuchon; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coagulation; elasticity; platelets; rheology; transfusion; Transfusion medicine; Transfusionsmedicin;

    Sammanfattning : Platelets play an important role in the haemostatic process in order to seal damaged blood vessels. The platelets form a platelet plug at the damaged area and prevent blood loss. Once the damage to the vessel wall has been covered, the platelets retract the coagulum, to allow the blood to flow freely in the vessel. LÄS MER

  7. 20. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Författare :Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Sammanfattning : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. LÄS MER