Sökning: "platelets activation"
Visar resultat 11 - 15 av 128 avhandlingar innehållade orden platelets activation.
11. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research
Sammanfattning : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. LÄS MER
12. Sources of Arachidonic Acid in Platelets, Bone, Marrow and Gastrointestinal Tract
Sammanfattning : This study investigates pathways by which the eicosanoid precursor pools in the platelets, bone marrow and the gastrointestinal (GI) mucosa are acquired and regulated, and in this context some aspects on the interaction between triglyceride (TG)-rich lipoproteins and platelets. 1. LÄS MER
13. Role of platelets and neutrophils in regulating trypsinogen activation and tissue damage in acute pancreatitis
Sammanfattning : Acute pancreatitis is an inflammatory disease characterized by a diverse spectrum of clinical presentations ranging from a mild and self-limiting to a severe and systemic disorder. The relationship between inflammation and proteolytic activation in pancreatitis is an elusive issue. LÄS MER
14. Platelet activation and aggregation: Clinical and experimental studies
Sammanfattning : Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim of this thesis was to identify and evaluate current and potential methods to reduce and prevent bleeding complications in patients with ongoing antiplatelet therapy. LÄS MER
15. Novel Agonists and Antagonists of Platelet Receptors
Sammanfattning : Platelets are central for the primary haemostatis. The platelet has surface bound receptors that are vital for the platelet activation. LÄS MER