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Visar resultat 1 - 5 av 128 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Platelets : intracellular signalling and cellular interaction

    Författare :Magnus Grenegård; Hans Gyllenhammar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Activation of platelets is essential to prevent excessive blood loss at the site of vascular injury. These highly reactive cell fragments are also involved in several pathological conditions, in particular arterial thrombosis, which, in the coronary vessels, can lead to reduced blood flow, vessel occlusion and myocardial infarction. LÄS MER

  2. 2. Platelet Activation and Inhibition in Connection with Vascular Stents

    Författare :Kjeld Christensen; Rolf Larsson; Sten Husted; Uppsala universitet; []
    Nyckelord :Medicine; platelets; inhibition; activation; stents; ACS; Medicin;

    Sammanfattning : This thesis describes the Chandler loop, which makes it possible to conduct studies in vitro of molecular and cellular interactions between whole blood and stents. It was possible to monitor activation and inhibition of the cascades systems, leukocytes and platelets by combining different platelet inhibitors and heparin coating of stents. LÄS MER

  3. 3. Interactions between whole blood and TiO₂ surfaces with focus on adhesion and activation of PMN granulocytes

    Författare :Cecilia Eriksson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; titanium; TiO2; surface roughness; oxide thickness; wettability; whole blood; inflammation; wound healing; platelets; PMN granulocytes; adhesion; activation; receptor expression; respiratory burst.;

    Sammanfattning : Foreign materials come in contact with the human body more and more frequently. The surgical procedure of inserting an implant into the body will cause bleeding, evoke an inflammatory response and initiate a healing process, ultimately leading to acceptance or rejection of the material. LÄS MER

  4. 4. Crosstalk Between Activated Platelets and the Complement System

    Författare :Osama A. Hamad; Bo Nilsson; Kristina Ekdahl-Nilsson; Lennart Truedsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; activated platelets; TRAP; chondroitin sulfate; C1q; factor H; C4BP; C3; Compstatin; complement; platelet-leukocyte complexes; platelet microparticles; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. LÄS MER

  5. 5. Platelet activation and cytokine release during experimental extracorporeal circulation

    Författare :Katrin Adrian; Göteborgs universitet; []
    Nyckelord :ECMO; blood-biomaterial interaction; platelets; platelet activation; cytokines; systemic inflammatory response;

    Sammanfattning : .... LÄS MER