Sökning: "platelet-derived growth factors receptors PDGFRs"

Hittade 2 avhandlingar innehållade orden platelet-derived growth factors receptors PDGFRs.

  1. 1. Current Medical Treatment of Endocrine Pancreatic Tumors and Future Aspects

    Författare :Marie-Louise Fjällskog; Morten Vatn; Uppsala universitet; []
    Nyckelord :Medical sciences; pancreatic tumors; somatostatin analogs; cisplatin; etoposide; somatostatin receptors; immunohistochemistry; tyrosine kinase receptors; platelet-derived growth factors receptors PDGFRs ; c-kit; epidermal growth factor receptor EGFR ; MEDICIN OCH VÅRD; alfa-interferon; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : We treated 16 patients with somatostatin analogs combined with α-interferon and achieved a biochemical and/or radiological response in 56% (median duration 22 months). We consider this treatment a good alternative for patients who fail during chemotherapy or who do not want to/cannot receive cytotoxic drugs. LÄS MER

  2. 2. Exploring the role of PDGF-D in health and disease

    Författare :Hanna Gladh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The platelet-derived growth factors (PDGF) and their receptors (PDGFRs) regulate growth and migration in cell populations of mesenchymal origin. The PDGF signaling system is vital for development, in neural crest formation, in organogenesis, and in maturation of the microvasculature. In the adult, PDGFs are needed to maintain homeostasis. LÄS MER