Sökning: "platelet microparticles"

Visar resultat 11 - 15 av 24 avhandlingar innehållade orden platelet microparticles.

  1. 11. Cell derived microparticles : method development, and clinical and experimental studies

    Författare :Fariborz Mobarrez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cell derived microparticles (MP) are released from the cell membrane upon activation or apoptosis. They resemble their parent cell by exposing similar proteins or surface receptors. This enables identification of their cellular origin. LÄS MER

  3. 12. Abnormal coagulation and platelet function in patients with severe traumatic brain injury

    Författare :Michael Nekludov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Traumatic brain injury (TBI) is associated with a high mortality and severe long-term morbidity in survivors. TBI often affects previously healthy young persons, and represents one of the most common causes of death among younger patients. The outcome in general trauma patients has improved over the recent decades. LÄS MER

  4. 13. Microparticles in hemophilia : friend or foe? To improve hemostasis or to induce atherothrombosis?

    Författare :Yanan Zong; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : As one of the most well-known inherited bleeding disorders, hemophilia A (HA) is caused by the deficiency or dysfunction of coagulation factor VIII (FVIII). Patients with HA (PWHA) suffer from abnormal bleeding after injuries or surgeries, or even spontaneous bleeding in severe cases, particularly at joints and muscles. LÄS MER

  5. 14. Effects of lipid-lowering treatment on platelet function and hemostatic mechanisms in diabetic patients : influence of chronic kidney disease and inflammatory parameters

    Författare :Tora Almquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetes mellitus (DM) and chronic kidney disease (CKD) are both associated with increased cardiovascular morbidity and mortality, and the risk is even higher when they are concurrent. Both diseases are considered to be prothrombotic states with increased inflammatory activity and major disturbances in the hemostasis. LÄS MER

  7. 15. Studies of ADAMTS13 expression and activity in the kidney

    Författare :Ramesh Tati; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ADAMTS13; von WIllebrand factor; thrombotic thrombocytopenic purpura;

    Sammanfattning : Von Willebrand factor (VWF) is an abundant plasma glycoprotein involved in platelet adhesion and aggregation at sites of vascular injury. ADAMTS13 is the sole physiological VWF-cleaving protease, thus regulating the size of thrombus growth. LÄS MER