Sökning: "platelet assay"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden platelet assay.

  1. 1. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Författare :Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Sammanfattning : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. LÄS MER

  3. 2. Platelet adhesion and P-selectin surface expression

    Författare :Per A. Whiss; Nils Olav Solum; Linköpings universitet; []
    Nyckelord :divalent cations; ELISA; nicotine; nitric oxide; platelet adhesion; P-selectin; MEDICINE; MEDICIN;

    Sammanfattning : Upon injury in a blood vessel, platelets become activated and adbere to prevent blood loss. Activated platelets express adhesion molecules on their surface that also make leukocytes adhere to the injury. One such molecule, which also is expressed on endothelium, is the glycoprotein P-selectin. LÄS MER

  4. 3. Platelet function in diabetes mellitus : studies on postprandial platelet activation and aspirin treatment

    Författare :Galia Spectre; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetes mellitus (DM) is a prothrombotic disease which is associated with a high risk for cardiovascular events, especially in type 2 DM (T2DM). The aim of this work is to contribute to the improvement of cardiovascular risk in DM. LÄS MER

  5. 4. Plasminogen Activator Inhibitor 1 in Platelets - Studies of Synthesis, Activity, and Glycosylation Patterns

    Författare :Helén Brogren; Göteborgs universitet; []
    Nyckelord :PAI-1; platelets; plasma; fibrinolysis; synthesis; polymorphism; glycosylation; activity; platelet mRNA;

    Sammanfattning : Plasminogen activator inhibitor 1 (PAI-1) is the main physiological inhibitor of tissue-type plasminogen activator. Thus PAI-1 plays an important role in decreasing the fibrinolytic activity in human blood. PAI-1 is present in high concentrations in platelets and also in low concentrations in plasma, but the source of plasma PAI-1 is not known. LÄS MER

  7. 5. Studies of platelet function, and effects of aspirin and clopidogrel treatment

    Författare :Christina Perneby; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antiplatelet therapy with aspirin and clopidogrel is a cornerstone in cardiovascular prevention and lowers cardiovascular mortality and morbidity in patient with coronary artery disease (CAD). Mental stress and physical exertion can trigger acute coronary events and prothrombotic responses to stress may contribute to such triggering. LÄS MER