Sökning: "plasticitet"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet plasticitet.

1. 1. The relationship between overweight and depression in view of genes, environment and their joint influence

   Författare :Sofia H. Kanders; Cecilia Åslund; Kent W. Nilsson; Dan Larhammar; Nancy Pedersen; Uppsala universitet; []
   Nyckelord :depression; overweight; obesity; plasticity; pharmacogenetics; genetics; antidepressants; breastfeeding; bullying; depression; övervikt; obesitas; plasticitet; farmakogenetik; genetik; antidepressiva läkemedel; mobbning; amning; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Obesity and depression are known to often go hand in hand, but is this due to our genetic heritage, environmental factors or a combination thereof? With a neuroscientific approach, I have investigated the relationship between obesity and depression with the aim of bridging the different levels of research available in order to better understand this complex topic. Using data from a longitudinal cohort with adults, we analysed the genetic contribution to antidepressant response in Study I. LÄS MER

3. 2. Temporal dynamics of brain plasticity : characterizing brain structural changes during skill acquisition

   Författare :Tomás Mediavilla; Daniel Marcellino; Alexandra Badea; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Motor learning; brain plasticity; structural plasticity; magnetic resonance imaging; voxel-based morphometry; tractography; connectivity; motor cortex; posterior parietal cortex; cerebellum; vesicular glutamate transporter;

   Sammanfattning : Traditionally, structural plasticity in the human brain has been considered to follow a linear or asymptotic increase over the course of training. However, recent studies using structural MRI revealed transient increases in grey matter volume (GMV) with learning. LÄS MER

4. 3. Modelling of high strain rate plasticity and metal cutting

   Författare :Dan Wedberg; Jesper Hattel; Luleå tekniska universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Material Mechanics; Materialmekanik;

   Sammanfattning : Metal cutting is one of the most frequently used forming processes in the manufacturing industry. Extensive effort is made to improve its process and simulation has become an integrated part, not only in the product development process but also in the customer relations. LÄS MER

5. 4. Role of Neuroinflammation in Parkinson's Disease and Related Disorders

   Författare :Edoardo Brandi; Neural plasticitet och reparation; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha synuclein; Preformed fibrils; Microglia; Astrocyte; Neuroinflammation; Lipopolysaccharides; Parkinson Disease; Lewy Body Dementia; Multiple system atrophy; Synucleinopathies;

   Sammanfattning : Synucleinopathies are neurodegenerative disorders characterized by intracellular protein aggregates, progressive neurodegeneration, and neuroinflammation. Alpha-synuclein (a-syn) is the principal component of intracellular aggregates and can be modified by several mutations and post-translational modifications (PTMs), which can alter the protein structure affecting its aggregation, toxicity, and ability to spread. LÄS MER

7. 5. Alpha-synuclein: pathology, peripheral expression, and environmental interactions

   Författare :Caroline Haikal; Neural plasticitet och reparation; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease PD ; alpha-synuclein; Bacterial amyloids; Synucleinopathies; Gastrointestinal GI tract; DMSO;

   Sammanfattning : .... LÄS MER