Sökning: "plasmids"

Visar resultat 11 - 15 av 123 avhandlingar innehållade ordet plasmids.

  1. 11. Evolution of beta-lactam : resistance in Klebsiella pneumoniae

    Författare :Sara Hæggman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : K. pneumoniae is recognized as a common opportunistic pathogen. Numerous reports have been published worldwide on outbreaks in different healthcare settings. K. LÄS MER

  3. 12. Genomic organization and diversity of Clostridium botulinum group III : the bug behind animal botulism

    Författare :Hanna Skarin; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Botulism is caused by botulinum neurotoxins (BoNTs) produced by the spore forming strictly anaerobic bacterium Clostridium botulinum. Seven different types of BoNTs (type A-F) have so far been established on the basis of neutralization with different antibodies. LÄS MER

  4. 13. Studies in DNA immunization

    Författare :Cecilia Svanholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chlamydia pneumoniae; DNA vaccine; GM-CSF; HIV-1; hsp60; Nef; Rev; Tat; signal sequence;

    Sammanfattning : This thesis describes investigations and developments of DNA immunization techniques, which were applied in the study of two different pathogens; HIV-1 and Chlamydia pneumoniae. DNA vaccines, i.e. naked plasmid DNA encoding an antigen, represent a novel strategy for generating protective immunity against several infectious diseases. LÄS MER

  5. 14. Functional studies of plant hexokinases and development of genetic methods in the moss Physcomitrella patens

    Författare :Mikael Ulfstedt; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : In the field of biology, model systems are frequently used for practical reasons. Model organisms possess several features that make them easy to work with in a laboratory setting. In addition they usually have a host of established genetic tools that have been developed by the research community. LÄS MER

  7. 15. Strategies of gene and immune therapy for tumors and viral diseases

    Författare :Herman José Arteaga; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Intracellular cytokines; DNA vaccine-GM-CSF; HIV- 1; RNA interference;

    Sammanfattning : In the treatment of tumors and viral diseases such as HIV-1 infection, immunotherapeutic strategies do not seem to have enough capacity to eradicate an already established disease. However, these strategies could play a unique role as adjuvant treatments of therapies that eliminate the main tumor or viral load in order to avoid the relapse of the disease. LÄS MER