Sökning: "plasma profiling"

Visar resultat 16 - 20 av 64 avhandlingar innehållade orden plasma profiling.

1. 16. Array-based Autoantibody Profiling and Epitope Mapping

   Författare :Arash Zandian; Peter Nilsson; Jochen M. Schwenk; Maja Neiman; Morten Nielsen; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody; antigens; peptide; epitope mapping; autoimmunity; autoantibodies; microarrays; Bioteknologi; Biotechnology;

   Sammanfattning : Antibodies are a class of proteins that are made by the immune system to recognize harmful organisms and molecules. Their exceptional capability of specifically recognizing molecules has been investigated for over a century and information thereof has been utilized for a variety of applications including vaccine and generation of therapeutic antibodies. LÄS MER

3. 17. Gene and Protein Profiling of the Preeclamptic Placenta

   Författare :Magnus Centlow; Lund Obstetrik och gynekologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antigen presentation; APOA1; hemoglobin; immunohistochemistry; in situ hybridization; Microarray; 2D-PAGE; uterine artery bilateral notching;

   Sammanfattning : Aims State-of-the-art methodology was used to screen and profile the placenta, gene and protein expression, for changes related to preeclampsia (PE) and cases with increased resistance in the uterine arteries. Women with increased resistance in the uterine arteries have increased risk of developing PE. LÄS MER

4. 18. Studies on scavenger receptor class B type I and genes implicated in foam cell formation

   Författare :Per-Arne Svensson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; scavenger receptor class B type I; high-density lipoprotein; oxidized low-density lipoprotein; macrophages; expression profiling;

   Sammanfattning : The risk of atherosclerosis correlates with plasma levels of low-density lipoprotein (LDL) cholesterol and is inversely correlated to plasma levels of high-density lipoprotein (HDL) cholesterol. Accumulation of oxidized LDL (oxLDL) by arterial macrophages is a key event in the development of atherosclerosis. LÄS MER

5. 19. Mutation and immune profiling of non-small cell lung cancer

   Författare :Linnéa La Fleur; Johan Botling; Fernando López-Ríos; Uppsala universitet; []
   Nyckelord :Non-small cell lung cancer; Tumor microenvironment; Tumor-associated macrophages; Immune infiltrates; PD-L1; Mutation patterns; Immune therapy; MARCO; TP53; STK11; KRAS;

   Sammanfattning : Several novel therapies that target molecular alterations and immune checkpoints in lung cancer have been introduced in the last decade. Still, only a minority of patients obtain long term disease control and overall survival remains poor. LÄS MER

7. 20. Biogenesis, function and regulation of the type III secretion translocon of Yersinia pseudotuberculosis

   Författare :Salah I. Farag; Matthew S Francis; Jörgen Johansson; Åke Forsberg; Luís Jaime Mota; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; type III secretion system; translocation; translocon; regulation; bacteria-eukaryotic cell contact; cytokine profiling;

   Sammanfattning : Many Gram negative bacteria use type III secretion systems to cross-talk with eukaryotic cells. Type III secretion system assembly and function is tightly regulated. LÄS MER