Sökning: "plaques"

Visar resultat 16 - 20 av 310 avhandlingar innehållade ordet plaques.

  1. 16. Amyloid Maturation Patterns in Alzheimer's Disease - Novel chemical imaging of Aβ and Tau pathology

    Författare :Srinivas Koutarapu; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid β; Neurofibrillary Tangles; matrix-assisted laser desorption ionization-mass spectrometry imaging MALDI-MSI ; luminescent conjugated oligothiophenes; Alzheimer’s Disease; Neurodegeneration;

    Sammanfattning : Alzheimer’s disease (AD) accounts for approximately 70% of dementia cases in Sweden. It can be of genetic origin i.e. familial form (fAD), sporadic form (sAD). LÄS MER

  3. 17. Multimodal Chemical Imaging of Amyloid Plaque Pathology in Alzheimer’s Disease

    Författare :Wojciech Michno; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; beta-amyloid; electron microscopy; imaging mass spectrometry; lipids; luminescent conjugated oligothiophenes; matrix-assisted laser desorption ionization mass spectrometry MALDI-MS ; molecular imaging; nanoscale secondary ion mass spectrometry NanoSIMS ; neurodegeneration; peptides;

    Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia. AD has been linked to the aggregation of amyloid beta (Aβ) peptides into extracellular deposits, Aβ plaques. These are also found in cognitively unimpaired amyloid-positive (CU-AP) individuals, but these Aβ plaques are primarily diffuse in structure. LÄS MER

  4. 18. Imaging of subclinical atherosclerosis by B-mode ultrasound. Measurement reproducibility and assessment of atherosclerotic plaque occurrence, size and echogenicity in relation to cardiovascular disease

    Författare :Caroline Schmidt; Göteborgs universitet; []
    Nyckelord :atherosclerosis; intima-media thickness; reproducibility; plaque; echogenicity;

    Sammanfattning : Atherosclerosis is an insidious disease that in general has a very long clinical silent phase. This disease does not take place uniformly in the arterial tree, instead major sites for this disease process are the coronary arteries, carotid and cerebral arteries, aorta and the large arteries to the lower extremities. LÄS MER

  5. 19. T-cell specificity and regulation in atherosclerosis

    Författare :Anton Gisterå; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived macrophages and T-helper (Th) 1 cells to form lipid-laden atherosclerotic plaques in the artery wall. LÄS MER

  7. 20. Roles of Heparan Sulfate in Amyloid-β Pathology and Hypoxia

    Författare :Elina Hjertström; Jin-ping Li; Ulf Lindahl; Sally Stringer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; Alzheimer s disease; Aβ; Proteoglycan; Heparanase; Amyloid; Hypoxia; Cancer; Spalax; Biochemistry; Biokemi; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Heparan sulfate (HS) is a highly sulfated polysaccharide expressed on the cell surface and in the extracellular matrix, interacting with a large number of proteins. HS is implicated in human diseases, including different types of cancer and amyloid diseases such as Alzheimer's disease (AD). LÄS MER