Sökning: "placental transport"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden placental transport.

1. 1. Placental transport of glucose and amino acids in early pregnancy. Cellular mechanisms, regulation and relation to diabetes

   Författare :Anette Ericsson; Göteborgs universitet; []
   Nyckelord :placental transport; diabetes; first trimester; GLUT; system A; hyperglycemia;

   Sammanfattning : Despite strict glycemic control of the pregnant woman with type 1 diabetes fetal overgrowth is still common. The first trimester is often characterized by sub-optimal glucose levels and elevated HbA1C in early pregnancy is a predictor of fetal overgrowth. LÄS MER

3. 2. Calcium transport across the human placenta. The activity, expression and regulation of Ca2+ ATPase in normal and complicated pregnancies

   Författare :Hilja Strid; Göteborgs universitet; []
   Nyckelord :fetal growth; placental transport; human; pregnancy PTHrP 38-94 ; intrauterine growth restriction; diabetes; calcium;

   Sammanfattning : .... LÄS MER

4. 3. Molecular Mechanisms Underlying Abnormal Placentation in the Mouse

   Författare :Yang Yu; Reinald H. Fundele; Rolf Ohlsson; J. GRAHAM BURTON; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; IUGR; Placental phenotype; Placental hyperplasia; Diabetes; IHPD; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

   Sammanfattning : Placental development can be disturbed by various factors, such as mutation of specific genes or maternal diabetes. Our previous work on interspecies hybrid placental dysplasia (IHPD) and two additional models of placental hyperplasia, cloned mice and Esx1 mutants, showed that many genes are deregulated in placental dysplasia. LÄS MER

5. 4. Cytokines and lipids in pregnancy – effects on developmental programming and placental nutrient transfer

   Författare :Susanne Lager; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; amino acids; cytokines; developmental programming; free fatty acids; insulin resistance; interleukin-6; lipoprotein lipase; nutrient transport; placenta; toll-like receptor 4;

   Sammanfattning : Metabolic disturbances, in particular those associated with nutritional challenges, that take place during development, both in utero and early postnatal life, have long-lasting health consequences on an individual. The most pronounced evidence of these challenges is a deviation in birth weight. LÄS MER

7. 5. Transport of sodium and protons in the human placenta. Mechanisms in normal pregnancy and alterations in intrauterine growth restriction

   Författare :Martin Johansson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; placenta; Na K ATPase; Na H exchanger; H K ATPase; intrauterine growth restriction; BeWo cells; epithelial transport;

   Sammanfattning : The syncytiotrophoblast cell of the human placenta represents the interface between maternal and fetal blood supplies. This polarized epithelium consists of a maternal facing microvillous membrane (MVM) opposing a fetal facing basal membrane (BM). This unique syncytial cell is responsible for transfer of all nutrients to the developing fetus. LÄS MER