Sökning: "phytoestrogen and conformational changes"

Hittade 1 avhandling innehållade orden phytoestrogen and conformational changes.

1. 1. Molecular basis of estrogen receptor antagonism

   Författare :Nina Heldring; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Estrogen Receptor; antagonism; receptor signaling; phytoestrogen and conformational changes;

   Sammanfattning : Estrogen Receptors (ERs), ERα and ERβ, are responsible for mediating the physiological effects of the steroid hormone 17b-estradiol and structurally related compounds. ER signaling is a complex process where the combined effects of accessory proteins, known as coregulators, promoter characteristics and influence from other signaling systems, determine the cell-specific transcriptional response in a given situation. LÄS MER