Sökning: "photoconjugation."

Hittade 3 avhandlingar innehållade ordet photoconjugation..

  1. 1. Site-specific labeling of affinity molecules for in vitro and in vivo studies

    Författare :Anna Perols; Amelie Eriksson Karlström; Christian Hackenberger; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Affibody molecules; molecular imaging; site-specific labeling; solid phase peptide synthesis; IgG-binding domains; photoconjugation.; Bioteknologi; Biotechnology;

    Sammanfattning : The thesis is focused on site-specific labeling of affinity molecules for different applications where two types of binding proteins, Affibody molecules and antibodies, have been used. For the purpose of improving the properties of Affibody molecules for in vivo imaging, novel bi-functional chelators for radiolabeling using the radionuclide 111In were evaluated. LÄS MER

  3. 2. Nano- and Micro-sized Molecularly Imprinted Polymer Particles on Solid Surfaces

    Författare :Tripta Kamra; Synkrotronljusfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Molecularly imprinted polymers (MIPs) are artificial receptors made by imprinting template molecules in a polymer matrix followed by their removal through washing to obtain a specific and selective template cavities. This property of the MIPs have made them a very efficient material for diverse applications such as chromatography, purification, drug sensing, etc. LÄS MER

  4. 3. Generating Affinity Proteins for Biotechnological, Diagnostic and Therapeutic Applications

    Författare :Feifan Yu; Per-Åke Nygren; Lynne Regan; KTH; []
    Nyckelord :Protein engineering; Bioteknologi; Biotechnology;

    Sammanfattning : Protein engineering is a powerful tool to modify proteins to generate novel and desired properties that could be applied in biotechnological, diagnostics and therapeutic areas. In this thesis, both rational design and library based engineering principles have been exploited to develop affinity proteins with desired traits. LÄS MER