Sökning: "phospholipase D"

Visar resultat 26 - 29 av 29 avhandlingar innehållade orden phospholipase D.

  1. 26. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?

    Författare :Sandra Holt; Christopher J Fowler; Anders Bucht; Gunnar Tiger; Ruth A Ross; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; FAAH; anandamide; endocannabinoid; pH; inflammation; NSAID; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. LÄS MER

  3. 27. Plant pathogen defense: Signalling, resistance and cell death

    Författare :Oskar N. Johansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pseudomonas; cell death; pathogens; plant defense; hypersensitive response; glycolipid; reactive oxygen species; blumeria graminis; erysiphe pisi;

    Sammanfattning : Pathogenic microorganisms are present everywhere in nature and infect both animals and plants. Phytopathogenic microorganisms cause diseases on plants, and are responsible for crop loss amounting in the order billions of dollars annually. LÄS MER

  4. 28. Role of inositol pyrophosphates in pancreatic beta cell function

    Författare :Subu Surendran Rajasekaran; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inositol pyrophosphates are high energy diphosphate containing molecules that are ubiquitous in eukaryotic cells. They have been implicated in diverse cellular processes ranging from DNA repair, telomere length regulation, ribosome synthesis, cell cycle regulation and apoptosis to osmoregulation, phosphate homeostasis, insulin sensitivity, vesicle trafficking, cytoskeletal rearrangement and exocytosis. LÄS MER

  5. 29. The Lysosomal-Mitochondrial Axis Theory of Apoptosis

    Författare :Ming Zhao; Sten Orrenius; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : In many cases, apoptosis may be initiated by a minor lysosomal destabilization, which some time later is followed by a secondary, more pronounced, lysosomal rupture. After exposure to low concentrations of sphingosine, a lysosomotropic detergent, Jurkat and J774 cells underwenr apoptotic cell death, while cells exposed to higher concentrations of this agent showed necrosis. LÄS MER