Sökning: "phosphatidylserine"
Visar resultat 1 - 5 av 29 avhandlingar innehållade ordet phosphatidylserine.
1. Mechanisms and mediators of apoptosis : with special reference to hematological disorders
Sammanfattning : Life and death are inextricably entwined. Naturally occurring cell death or apoptosis is essential for the of homeostasis and serves to remove extraneous or dangerous cells in a swift and unobtrusive manner. work has demonstrated that such cell death is genetically regulated and transpires according to evolutionarily conserved pathways. LÄS MER
2. Structural and Functional Studies of Gas6
Sammanfattning : The vitamin K-dependent and ubiquitously expressed 82 kDa glycoprotein product of the growth-arrest-specific-gene 6, Gas6, shows 44% sequence identity to the anticoagulant protein, protein S. Both proteins share further the same domain organization. LÄS MER
3. Characterization of parameters influencing intracellular bioavailability and prediction of intracellular drug exposure
Sammanfattning : This thesis work investigates factors influencing intracellular drug disposition. An experimental method for measurement of intracellular bioavailability (Fic), was used throughout. Fic is defined as the ratio between the unbound drug concentration inside the cell and the compound concentration in the cell exterior. LÄS MER
4. Isolation and characterization of lipid-associated and neurosecretory polypeptides
Sammanfattning : Lipid-interacting proteins play important roles in all living organisms. This thesis focuses on isolation and characterization of an enzyme in the triacylglycerol biosynthesis (phosphatidic acid phosphatase, PAP), hydrophobic polypeptides in bile, and polypeptides in cerebrospinal fluid. LÄS MER
5. The Genetics of Systemic Lupus Erythematosus : The Specificity of IRF5 to SLE
Sammanfattning : The breakdown of self-tolerance is the main driving force behind susceptibility to SLE. When this occurs, T and B cells are activated in an uncontrolled manner and produce autoantibodies against self fragmented DNA, RNA and sometimes other parts of the cell such as cardiolipin, phosphatidylserine, etc. LÄS MER