Sökning: "phosphatidylinositol 3-kinase"
Visar resultat 11 - 15 av 44 avhandlingar innehållade orden phosphatidylinositol 3-kinase.
11. Regulation of neutrophil apoptosis
Sammanfattning : The human neutrophil is the most abundant granulocyte and the major type of cell involved in an acute inflammatory response. Neutrophils are armed with various systems of enzymes, that can find and kill pathogens, but unfortunately, these "weapons" cannot distinguish between the host tissues and the "invaders. LÄS MER
12. Protease proforms as hematopoietic regulators
Sammanfattning : A common feature in myeloid leukemia is suppression of normal hematopoiesis, leading to infections, bleeding and anemia. It has been suggested for a long time that leukemic cells possess a growth-advantage by overproducing an inhibitor - a leukamia associated inhibitor. LÄS MER
13. Role of Cell-cell Interactions and Palmitate on β-cells Function
Sammanfattning : The islets of Langerhans secrets insulin in response to fluctuations of blood glucose level and efficient secretion requires extensive intra-islet communication. Secretory failure from islets is one of the hallmark in progression of type 2 diabetes. LÄS MER
14. Positional Cloning of Disease Causing Genes : A Genetic Study of Obesity, Ichthyosis Prematurity Syndrome and Meniere's Disease
Sammanfattning : Positional cloning is a method to identify genes from their position in the genome without prior knowledge about function. We used this approach to investigate the basis for three distinct genetic disorders; Obesity, Ichthyosis Prematurity Syndrome and Meniere's disease. LÄS MER
15. β-adrenergic regulation of glucose transporters
Sammanfattning : The transport of glucose across the plasma membrane is a fundamental mechanism to provide cells with its basic requirements for energy yielding processes. It is also vital for clearing glucose from blood into tissues, a process normally stimulated by the hormone insulin in mammals. LÄS MER
