Sökning: "phosphatidylcholine"

Visar resultat 1 - 5 av 37 avhandlingar innehållade ordet phosphatidylcholine.

  1. 1. Enzymatic Synthesis of Mixed Acid Phospholipids

    Författare :Dietlind Adlercreutz; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lysophosphatidylcholine; phosphatidylcholine; acyl migration; equilibrium; organic solvent; lipase; phospholipase; Biotechnology; Bioteknik;

    Sammanfattning : Mixed acid phospholipids are valuable compounds, which are used mainly in membrane- and lipoprotein research and in liposome technology. The chemical synthesis of these special lipids is rather difficult and involves both toxic chemicals and harsh reaction conditions, which makes the products less attractive for medical and biological applications. LÄS MER

  3. 2. Studies of Experimental Bacterial Translocation

    Författare :Anders Stenbäck; Cecilia Johnsson; Staffan Meurling; Bengt Jeppsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Intestinal barrier; short bowel syndrome; small bowel transplantation; mesenteric lymph nodes; gadolinium chloride; T cell inactivation; glutamine; phosphatidylcholine; rat; Thiry-Vella loop; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : One of the main obstacles to maintaining patients with short bowel syndrome on parenteral nutrition, or successfully transplanting these patients with a small bowel graft, is the many severe infections that occur. Evidence is accumulating that translocating bacteria from the patient’s bowel causes a significant part of these infections. LÄS MER

  4. 3. Development of Enhanced Analytical Methodology for Lipid Analysis from Sampling to Detection : A Targeted Lipidomics Approach

    Författare :Giorgis Isaac; Jonas Bergquist; Karin Markides; Monica Waldebäck; William Christie; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; electrospray ionization; lipids; liquid chromatography; mass spectrometry; pesticides; phosphatidylcholine; pressurized fluid extraction; sphingomyelin; sulfatides; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Sammanfattning : This thesis covers a wide range of analytical method development for lipid analysis in complex biological samples; from sample preparation using pressurized fluid extraction (PFE) and separation with reversed phase capillary liquid chromatography (RP-LC) to detection by electrospray ionization mass spectrometry (ESI/MS) and tandem MS.The requirements for fast, reliable and selective extraction methods with minimal usage of solvents have accelerated the development of new extraction techniques. LÄS MER

  5. 4. Methodological and clinical evaluation of the alcohol marker phosphatidylethanol (PEth)

    Författare :Lisa Walther; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :alcohol; alcohol marker; alcohol use disorder; phosphatidylethanol; PEth; phosphatidylcholine; alcohol use; gastric bypass; LC-MS MS;

    Sammanfattning : .... LÄS MER

  7. 5. Lecithin-Based Microemulsions for Pharmaceutical use - Phase behavior and Solution Structure

    Författare :Christian von Corswant; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; felodipine; solubilization; drug delivery; self-diffusion NMR; alkylmaltoside; microstructure; isopropyl myristate; triglyceride; soybean phosphatidylcholine; Microemulsion; lecithin; Livsmedelsteknik;

    Sammanfattning : Microemulsions are thermodynamically stable, transparent solutions of water, oil and amphiphile(s). It is possible to incorporate large amounts of oil in microemulsions, which makes them interesting for use as a drug delivery vehicle for water insoluble drugs. A prerequisite for pharmaceutical use, however, is a low toxicity of the composition. LÄS MER