Sökning: "phosphate drug"
Visar resultat 1 - 5 av 45 avhandlingar innehållade orden phosphate drug.
1. Computational Modelling in Drug Discovery : Application of Structure-Based Drug Design, Conformal Prediction and Evaluation of Virtual Screening
Sammanfattning : Structure-based drug design and virtual screening are areas of computational medicinal chemistry that use 3D models of target proteins. It is important to develop better methods in this field with the aim of increasing the speed and quality of early stage drug discovery. LÄS MER
2. Submicron Calcium Phosphate Spheres for Biomedical Applications : Synthesis and Use
Sammanfattning : Calcium phosphate spheres as biomaterials have been attracting attention in recent years. Calcium phosphate occurs naturally in bone, and a hollow structure could be advantageous for drug loading and release. LÄS MER
3. Porous Amorphous Calcium Carbonate and Phosphate : Synthesis and Application
Sammanfattning : The synthesis of porous amorphous calcium carbonate (ACC) and porous amorphous calcium phosphate (ACP) was developed in this thesis. Porous ACC with specific Brunauer–Emmett–Teller (BET) surface area of >350 m2/g was synthesized using a surfactant free approach. The high surface area of porous ACC was related to its nanostructure. LÄS MER
4. The biological and physical performance of high strength dicalcium phosphate cement in physiologically relevant models
Sammanfattning : The chemical properties of calcium phosphate cements (CPCs) are very similar to the mineral phase of bone. CPCs are, consequently, very effective substrates (scaffolds) for tissue engineering; bone and stem cells attach readily, and can proliferate and differentiate to form new bone tissue. LÄS MER
5. Injectable calcium sulphate and calcium phosphate bone substitutes
Sammanfattning : Two formulations of biphasic injectable bone substitutes have been developed for the treatment of bone defects and stabilisation of fragility fractures. The first formulation consists of a calcium sulphate matrix with embedded hydroxyapatite (HA) particles to provide osteoconductivity. LÄS MER