Sökning: "pharmacological preconditioning"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden pharmacological preconditioning.
Sammanfattning : Ischemic and traumatic brain damage are major causes of disability and death. While much effort has been spent to develop pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. LÄS MER
Sammanfattning : Traumatic and ischemic brain damage are major causes of disability and death. While much effort has been spent on developing pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. LÄS MER
3. Myocardial ischemia-reperfusion and cardioprotection. A study with microdialysis in a porcine model
Sammanfattning : The studies in this thesis are based on questions raised in the clinical setting. Perioperative myocardial ischemia occurs more often than recognized. This may lead to myocardial infarction, increased morbidity, mortality, and health care costs. LÄS MER
4. The importance of nitric oxide bioavailability and endothelial mechanisms for cardioprotection by pharmacological intervention during myocardial ischaemia and reperfusion
Sammanfattning : Myocardial ischaemia initiates complex severe cellular changes and, after a critical time period, myocardial cell death. Despite that restitution of coronary blood flow is an absolute pre-requisite for tissue survival, myocardial reperfusion per se will also increase irreversible damage in the jeopardised myocardium. LÄS MER
Sammanfattning : Ischemia and trauma are two clinical problems characterized by a common response: inflammation and potentially deleterious effects on the organism. Surgery is a form of trauma, and the most advanced surgical operations, including open heart surgery, aortic surgery, and organ transplantation, cause trauma and ischemia of the cardiovascular system. LÄS MER