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Visar resultat 1 - 5 av 30 avhandlingar som matchar ovanstående sökkriterier.
1. Towards application of activated carbon treatment for pharmaceutical removal in municipal wastewater
Sammanfattning : Many pharmaceuticals are found in municipal wastewater effluents due to their persistence in the human body as well as in conventional wastewater treatment processes. This discharge to the environment can lead to adverse effects in aquatic species, such as feminization of male fish. LÄS MER
2. Design, Synthesis and Thermodynamic Studies of Galectin Ligands
Sammanfattning : The signaling within and between cells in biology is governed by molecular recognition between natural or synthetic ligands and proteins. This thesis project aimed to investigate the thermodynamic properties of specific interaction between synthetic ligands and galectin proteins. LÄS MER
3. Interrogation of drug effects on the lipid composition of single cells and Drosophila brain using ToF-SIMS imaging
Sammanfattning : Lipids are essential for all living organisms on Earth. The most important function of lipids is that they act as the building blocks of cellular membranes. Lipids consist of polar head groups and non-polar tail groups and assemble into bilayer structures to create cell and organelle membranes. LÄS MER
4. Pharmacometric Models in Anesthesia and Analgesia
Sammanfattning : Modeling is a valuable tool in drug development, to support decision making, improving study design, and aid in regulatory approval and labeling. This thesis describes the development of pharmacometric models for drugs used in anesthesia and analgesia. LÄS MER
5. The mucus layer and other barriers to intestinal drug absorption
Sammanfattning : The extraepithelial mucus layer acts as a barrier to the absorption and diffusion of drugs. Three in vitro models have been used for studies of this and other intestinal barriers to drug transport. A drug absorption model based on monolayers of the mucus-producing human intestinal goblet HT29-H cell line was developed. LÄS MER