Sökning: "pharmaceutical mixtures"

Visar resultat 6 - 10 av 33 avhandlingar innehållade orden pharmaceutical mixtures.

  1. 6. Engineering of Native Cellulose Structure for Pharmaceutical Applications : Influence of Cellulose Crystallinity Index, Surface Area and Pore Volume on Sorption Phenomena

    Författare :Albert Mihranyan; Ragnar Ek; Maria Strømme; Hans Leuenberger; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; microcrystalline cellulose; Cladophora sp. algae; crystallinity index; surface area and pore volume; fractals; stability; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Cellulose powders from various sources were manufactured and characterized to investigate the influence of their crystallinity index, surface area, and pore volume on sorption phenomena and the relevant pharmaceutical functionality. The influence of the cellulose crystallinity index on moisture sorption was important at low and intermediate relative humidities. LÄS MER

  3. 7. Particle interactions and internal tablet structure : Factors affecting the mechanical strength of pharmaceutical compacts

    Författare :Helena Olsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Sammanfattning : A simple tablet model was utilised to identify parameters responsible for tablet compactibility. In this model tablets were considered as homogeneous and isotropic aggregates of individual spherical particles. If the particles were located close enough to each other, interparticulate bonds were assumed to be developed. LÄS MER

  4. 8. Studies on the characterization of powders and powder mixtures

    Författare :Karin Malmqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  5. 9. New Concepts in Administration of Drugs in Tablet Form : Formulation and Evaluation of a Sublingual Tablet for Rapid Absorption, and Presentation of an Individualised Dose Administration System

    Författare :Susanne Bredenberg; Christer Nyström; Carla Caramella; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Interactive mixture; Dose homogeneity; Disintegration; Bioadhesion; Oromucosal delivery; Sublingual tablet; Rapid absorption; Individual dosage; Drug dispensing device; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : This thesis presents two new concepts in oral drug administration and the results of evaluation of some relevant formulation factors.Investigation into improving the homogeneity of mixtures for tableting indicated that it may be possible to obtain interactive dry mixtures of micronised drugs containing drug proportions as low as 0.015% w/w. LÄS MER

  7. 10. Studies on a Novel Powder Formulation for Nasal Drug Delivery

    Författare :Nelly Fransén; Erik Björk; Katarina Edsman; Lars Hovgaard; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nasal drug delivery; nasal powder spray; interactive mixture; mucoadhesion; sodium starch glycolate; superdisintegrant; bioavailability; clinical trial; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Nasal administration has potential for the treatment of indications requiring a fast onset of effect or for drugs with low oral bioavailability. Liquid nasal sprays are relatively common, but can be associated with suboptimal absorption from the nasal cavity; this thesis shows that nasal absorption can be significantly enhanced with a dry powder formulation. LÄS MER