Sökning: "pet human"

Visar resultat 1 - 5 av 113 avhandlingar innehållade orden pet human.

1. 1. Translational PET imaging of inflammation

   Författare :Emmi Puuvuori; Olof Eriksson; Tove Grönroos; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET imaging; Nuclear Medicine; Inflammation; Translational Medicine;

   Sammanfattning : Inflammation is our body’s sophisticated defense mechanism against invading pathogens, traumas, and tumors. Repeatable and non-invasive monitoring of inflammation process would open opportunities to improve our knowledge of several diseases and enable assessment of personalized treatments. LÄS MER

3. 2. Regulation of Ovarian Aromatase: Studies by Aromatase Assays in vitro and in vivo

   Författare :Dmitrijus Kirilovas; Mats Brännström; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; aromatase; human; granulosa cells; 11C-vorozole; active site; allosteric configuration; in vitro; in vivo; PET; androgens; rat; estrous cycle.; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

   Sammanfattning : An in vitro method was developed for measuring aromatase, based on binding of competitive aromatase inhibitor [11C]vorozole to the active site of the enzyme. [11C]Vorozole displayed high, specific binding in vitro to human placenta and human granulosa cells (GC), both fresh and frozen/thawed cells, provided correct procedures were used. LÄS MER

4. 3. [68Ga]Exendin-4: Bench-to-Bedside : PET molecular imaging of the GLP-1 receptor for diabetes and cancer

   Författare :Ram kumar Selvaraju; Olof Eriksson; Olle Korsgren; Lars Johansson; Martin Gotthardt; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; [68Ga]Exendin-4; beta cell imaging; insulinoma; dosimetry;

   Sammanfattning : Diabetes epidemic is underway. Beta cell dysfunction (BCF) and loss of beta cell mass (BCM) are known to be key events in its progression. Currently, there are no reliable techniques to estimate or follow the loss of BCM, in vivo. LÄS MER

5. 4. Image Quality Optimisation and Dose Management in CT, SPECT/CT, and PET/CT

   Författare :Marcus Söderberg; Malmö Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CT; SPECT; PET; dosimetry; image quality; optimisation; dose reduction; automatic exposure control; contrast medium; phantom; image reconstruction; human observer;

   Sammanfattning : The significant increase in the use of CT, alone or combined with SPECT or PET, has raised concerns about patient radiation exposure and the consequent increased risk of malignancy later in life. The overall objective of this work was to evaluate and optimise different approaches for minimising patient radiation absorbed dose and maintaining or improving image quality in CT, SPECT/CT, and PET/CT. LÄS MER

7. 5. Modalities of Mind : Modality-specific and nonmodality-specific aspects of working memory for sign and speech

   Författare :Mary Rudner; Jerker Rönnberg; Alan Baddeley; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cognition; sign language; working memory; fMRI; PET; disability research; Korttidsminne; teckenspråk; Cognitive science; Kognitionsvetenskap;

   Sammanfattning : Language processing is underpinned by working memory and while working memory for signed languages has been shown to display some of the characteristics of working memory for speech-based languages, there are a range of anomalous effects related to the inherently visuospatial modality of signed languages. On the basis of these effects, four research questions were addressed in a series of studies:1. LÄS MER